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坦纳氏预测成年身高公式低估了印度裔亚洲人的最终身高——一项横断面观察性研究。

Tanner's Target Height Formula Underestimates Final Height in Asian Indians - A Cross-sectional Observational Study.

作者信息

Atluri Sridevi, Bharathidasan Kavya, Sarathi Vijaya

机构信息

Department of Endocrinology, Vydehi Institute of Medical Sciences and Research Center, Bengaluru, Karnataka, India.

出版信息

Indian J Endocrinol Metab. 2018 Jul-Aug;22(4):441-444. doi: 10.4103/ijem.IJEM_92_18.

Abstract

INTRODUCTION

Target height (TH) calculation by Tanner's formula has been shown to be inaccurate in many countries However, there is no published data on the accuracy of TH calculation by Tanner's formula in Indians. Hence, this study was conducted to assess whether Tanner's TH formula is an accurate tool to predict final height in Asian Indian population and to identify new TH formulae or models to better fit Indian population.

MATERIAL AND METHODS

This is a cross-sectional, questionnaire-based study conducted in a tertiary care hospital from South India. A total of 396 questionnaires were randomly distributed to undergraduate medical students who were instructed beforehand to get their heights and heights of their parents and siblings between the age of 18 to 24 years of age measured by a nearby pediatrician. From 396 questionnaires, data of 481 young adults and their parents were obtained. Target height was calculated by Tanner's formula and compared with attained height.

RESULTS

The study comprised of 197 males and 284 females. Sons and daughters were 2.34 ± 7.19 cm and 1.58 ± 5.68 cm taller than TH. Son's height had best correlation with TH ( = 0.408), whereas daughter's height had best correlation with maternal height ( = 0.560). Both males (0.263 vs 0.365) and females (0.319 vs 0.560) had relatively weaker correlation with paternal heights than maternal heights. Target height explained 29.7% and 16.7% of variance in daughter's and son's height, respectively. Using the parental heights as variables, multiple regression yielded 50.03 + 0.172 (father's height) +0.510 (mother's height) and 74.09 + 0.236 (father's height) +0.377 (mother's height) as the best models to predict daughter's and son's height, respectively.

CONCLUSION

Our study suggests that Tanner's TH formula underestimates final attainable height in Asian Indians.

摘要

引言

在许多国家,通过坦纳公式计算目标身高(TH)已被证明是不准确的。然而,关于坦纳公式在印度人当中计算目标身高准确性的公开数据并不存在。因此,本研究旨在评估坦纳的目标身高公式是否是预测亚洲印度人群最终身高的准确工具,并确定更适合印度人群的新目标身高公式或模型。

材料与方法

这是一项在印度南部一家三级护理医院进行的基于问卷调查的横断面研究。总共向本科医学生随机发放了396份问卷,这些学生事先被要求让附近的儿科医生测量他们18至24岁之间的身高以及他们父母和兄弟姐妹的身高。从396份问卷中,获得了481名年轻人及其父母的数据。通过坦纳公式计算目标身高,并与实际达到的身高进行比较。

结果

该研究包括197名男性和284名女性。儿子和女儿比目标身高分别高2.34±7.19厘米和1.58±5.68厘米。儿子的身高与目标身高的相关性最佳(=0.408),而女儿的身高与母亲身高的相关性最佳(=0.560)。男性(0.263对0.365)和女性(0.319对0.560)与父亲身高的相关性均比与母亲身高的相关性弱。目标身高分别解释了女儿身高和儿子身高方差的29.7%和16.7%。以父母身高为变量,多元回归得出分别预测女儿身高和儿子身高的最佳模型为50.03 + 0.172(父亲身高)+0.510(母亲身高)和74.09 + 0.236(父亲身高)+0.377(母亲身高)。

结论

我们的研究表明,坦纳的目标身高公式低估了亚洲印度人的最终可达到身高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36cd/6085975/cb1baf7faa72/IJEM-22-441-g001.jpg

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