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Vaccine. 2018 Sep 25;36(40):6022-6029. doi: 10.1016/j.vaccine.2018.08.001. Epub 2018 Aug 24.
Although the World Health Organization recommends universal rotavirus immunization, uptake of the vaccine is low in Poland and Hungary, where it is not covered by the National Immunization Program. This study aimed to quantify mothers' preferences for vaccines preventing children's diarrheal illness and to examine whether willingness to vaccinate varies with working status.
Mothers of children aged <3 years living in Poland and Hungary completed an online discrete-choice experiment survey. In each of 9 choice questions, respondents indicated whether they preferred no vaccination or one of two hypothetical vaccine profiles described in terms of 6 features. Vaccine preference parameters were estimated for working and non-working mothers using a random-parameter logit model and were used to calculate the relative importance of changes in vaccine features.
350 mothers in Poland and 350 mothers in Hungary were surveyed. Of the attributes evaluated, changes in vaccine cost were most important in both countries, followed by changes in severity of illness prevented, vaccine effectiveness, mode of administration, duration of illness prevented, and number of doses. Mothers in both countries had a strong preference for vaccination versus no vaccination, which was more pronounced among working mothers. In Poland, working mothers placed less weight on effectiveness, illness severity, and cost than non-working mothers and were more likely to rate disruptions in work, child care, and routines as important reasons to vaccinate. In Hungary, working mothers were statistically significantly less likely to opt out of vaccination than non-working mothers. Preference for vaccination itself, relative to improving vaccine effectiveness (from 50% to 90% effective), was 7 times greater among working than among non-working mothers in Poland but was not considerably different between working and non-working mothers in Hungary.
Polish and Hungarian working mothers are more likely to vaccinate children against diarrheal illness than non-working mothers.
尽管世界卫生组织建议普遍接种轮状病毒疫苗,但在波兰和匈牙利,由于该疫苗未被纳入国家免疫计划,其接种率较低。本研究旨在量化母亲对预防儿童腹泻疾病疫苗的偏好,并研究其接种意愿是否因工作状态而异。
波兰和匈牙利年龄<3 岁儿童的母亲完成了一项在线离散选择实验调查。在 9 个选择问题中,每位受访者都表示他们是否愿意选择不接种疫苗或两种假设疫苗中的一种,这两种疫苗都以 6 种特征来描述。使用随机参数对数模型为工作和非工作母亲估计疫苗偏好参数,并用于计算疫苗特征变化的相对重要性。
在波兰调查了 350 名母亲,在匈牙利调查了 350 名母亲。在所评估的属性中,疫苗成本的变化在两个国家都最为重要,其次是预防疾病严重程度、疫苗有效性、给药方式、预防疾病持续时间和剂量数的变化。与不接种疫苗相比,两国的母亲都强烈倾向于接种疫苗,其中工作母亲的偏好更为明显。在波兰,工作母亲对疫苗有效性、疾病严重程度和成本的重视程度低于非工作母亲,并且更有可能将工作、儿童保育和日常生活中断视为接种疫苗的重要原因。在匈牙利,工作母亲比非工作母亲更不可能选择不接种疫苗。与提高疫苗有效性(从 50%提高到 90%有效)相比,波兰工作母亲对接种疫苗本身的偏好是不工作母亲的 7 倍,但与匈牙利的工作母亲和非工作母亲相比,这种偏好并没有明显差异。
与非工作母亲相比,波兰和匈牙利的工作母亲更有可能为孩子接种预防腹泻疾病的疫苗。