Waters Darragh K, Elliott Jessie A, O'Duffy Fergal, O'Dwyer Tadgh
Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin, and St. James's Hospital, Dublin, Ireland.
Department of Otorhinolarynogology, Mater Misercordiae University Hospital, Dublin, Ireland.
J Surg Case Rep. 2018 Aug 20;2018(8):rjy222. doi: 10.1093/jscr/rjy222. eCollection 2018 Aug.
A 64-year-old male presented with a 2-month history of sudden onset dysphonia. Endoscopic evaluation of the larynx revealed a complete right vocal cord palsy. Computed tomography of the neck revealed a mass medial to the right thyroid associated with the cricoid cartilage. Histologic examination confirmed high-grade chondrosarcoma. The patient underwent right-sided hemicricoidectomy with tracheal flap reconstruction, right thyroid lobectomy and partial oesophagectomy with primary anastomosis followed by adjuvant radiation therapy. He is currently being followed as an outpatient with no evidence of disease. High-grade chondrosarcoma of the larynx is an exceedingly rare tumour, associated with a poor prognosis. Current best evidence suggests primary surgical resection with negative margins. There is a lack of evidence to guide post-operative management of high-grade chondrosarcoma. They have a poor prognosis following surgical resection and a 10-year survival rate of 29%.
一名64岁男性，突发声音嘶哑2个月。喉镜内镜检查显示右侧声带完全麻痹。颈部计算机断层扫描显示右侧甲状腺内侧有一肿物，与环状软骨相关。组织学检查确诊为高级别软骨肉瘤。患者接受了右侧半环状软骨切除术加气管瓣重建术、右侧甲状腺叶切除术及部分食管切除术并一期吻合，随后接受辅助放疗。目前他作为门诊患者接受随访，无疾病证据。喉高级别软骨肉瘤是一种极其罕见的肿瘤，预后较差。目前最佳证据表明应进行切缘阴性的原发性手术切除。缺乏指导高级别软骨肉瘤术后管理的证据。手术切除后其预后较差，10年生存率为29%。
