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意大利西西里岛一例由蜱传脑炎病毒引起的致命蜱传脑炎:IgG阳性/IgM阴性反应的病例?

A lethal Tick-Borne Encephalitis (TBE) due to TBE Virus in Sicily (Italy): a case of IgG+/IgM- response?

作者信息

Ventura Spagnolo E, Mondello C, Roccuzzo S, Cardia L, Raffino C

机构信息

Legal Medicine Section, Department for Health Promotion and Mother-Child Care, University of Palermo, Palermo.

Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina.

出版信息

Clin Ter. 2018 Jul-Aug;169(4):e145-e148. doi: 10.7417/T.2018.2069.

DOI:10.7417/T.2018.2069
PMID:30151545
Abstract

Tick-borne encephalitis (TBE) is an important viral infection of the central nervous system with high morbidity and mortality. With the increase of tourism TBE is becoming a problem also outside endemic regions. Italy is considered a country with low incidence of TBE and geographically restricted to the central and north eastern part of the country. In the south of Italy there is no evidence of disease presence, but neither is there much evidence of its absence. We report our experience about a lethal case of meningoencephalitis with a single-phase clinical course of the disease likely due to TBEV infection in a 13-year-old man. This is the first report of an autochthonous case of TBE in Sicily, region in the in Southern Italy.

摘要

蜱传脑炎(TBE)是一种重要的中枢神经系统病毒感染,具有高发病率和死亡率。随着旅游业的发展,TBE在非流行地区也日益成为一个问题。意大利被认为是TBE发病率较低的国家,地理上局限于该国中部和东北部。在意大利南部,没有疾病存在的证据,但也没有太多不存在该病的证据。我们报告了一例13岁男性因TBEV感染导致的单相临床病程的致死性脑膜脑炎病例。这是意大利南部西西里岛首例本土TBE病例报告。

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