Shi Xiaomin, Wang Shaolin
College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Sheng Wu Gong Cheng Xue Bao. 2018 Aug 25;34(8):1234-1245. doi: 10.13345/j.cjb.180177.
World Health Organization has recognized antibiotic resistance is one of the serious threats to public health and food-safety in the 21st century. Recently, the antibiotic resistance gene (ARG) has been widely considered as a new pollutant. Now, many studies suggested that animal farm is one of the major reservoirs of ARGs. Antibiotic resistance bacteria and antibiotic resistance genes enter the environment along with animal excrement, accelerating the spread of ARGs in the environment. In the livestock and poultry breeding environment, ARGs and antibiotic resistant bacteria could be transmitted to humans through the food chain, water or air, posing a great threat to public health. This review highlights the prevalence of antibiotic resistant bacteria and antibiotic resistant genes in livestock-breeding environment, the retention and spread of ARGs and the method used to study the antibiotic resistance, which will provide certain support for risk assessment of antimicrobial resistance in food animal breeding environment.
世界卫生组织已认识到抗生素耐药性是21世纪对公众健康和食品安全的严重威胁之一。最近，抗生素抗性基因（ARG）已被广泛视为一种新污染物。现在，许多研究表明，养殖场是ARG的主要储存库之一。抗生素抗性细菌和抗生素抗性基因随动物粪便进入环境，加速了ARG在环境中的传播。在畜禽养殖环境中，ARG和抗生素抗性细菌可通过食物链、水或空气传播给人类，对公众健康构成巨大威胁。本文综述了畜禽养殖环境中抗生素抗性细菌和抗生素抗性基因的流行情况、ARG的留存与传播以及研究抗生素抗性的方法，这将为食用动物养殖环境中抗菌药物耐药性的风险评估提供一定支持。
