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Emerging therapeutic potential of glycine in cardiometabolic diseases: dual benefits in lipid and glucose metabolism.

作者信息

Rom Oren, Villacorta Luis, Zhang Jifeng, Chen Y Eugene, Aviram Michael

机构信息

Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan Medical Center, Ann Arbor, Michigan, USA.

The Lipid Research Laboratory, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.

出版信息

Curr Opin Lipidol. 2018 Oct;29(5):428-432. doi: 10.1097/MOL.0000000000000543.

DOI:10.1097/MOL.0000000000000543
PMID:30153136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6198663/
Abstract
摘要

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Pro-atherogenic and pro-oxidant crosstalk between adipocytes and macrophages.脂肪细胞与巨噬细胞之间致动脉粥样硬化和促氧化的相互作用。
Eur J Nutr. 2019 Mar;58(2):879-893. doi: 10.1007/s00394-018-1729-7. Epub 2018 May 26.
2
Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors.补充 N-乙酰半胱氨酸和甘氨酸的饮食可改善老年小鼠的心血管功能:炎症和线粒体因素。
J Gerontol A Biol Sci Med Sci. 2018 Aug 10;73(9):1167-1177. doi: 10.1093/gerona/gly034.
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Branched-chain amino acids and atherosclerosis: friends or foes?支链氨基酸与动脉粥样硬化:是友还是敌?
Curr Opin Lipidol. 2018 Apr;29(2):166-169. doi: 10.1097/MOL.0000000000000494.
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Leucine supplementation attenuates macrophage foam-cell formation: Studies in humans, mice, and cultured macrophages.亮氨酸补充可减轻巨噬细胞泡沫细胞形成:在人体、小鼠和培养的巨噬细胞中的研究。
Biofactors. 2018 May;44(3):245-262. doi: 10.1002/biof.1415. Epub 2018 Feb 5.
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Glycine enhances expression of adiponectin and IL-10 in 3T3-L1 adipocytes without affecting adipogenesis and lipolysis.甘氨酸可增强 3T3-L1 脂肪细胞中脂联素和白细胞介素-10 的表达,而不影响脂肪生成和脂肪分解。
Amino Acids. 2018 May;50(5):629-640. doi: 10.1007/s00726-018-2537-3. Epub 2018 Jan 22.
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Serum and plasma amino acids as markers of prediabetes, insulin resistance, and incident diabetes.血清和血浆氨基酸作为糖尿病前期、胰岛素抵抗和新发糖尿病的标志物。
Crit Rev Clin Lab Sci. 2018 Jan;55(1):21-32. doi: 10.1080/10408363.2017.1414143. Epub 2017 Dec 14.
7
Insulin resistance and glycine metabolism in humans.人体胰岛素抵抗与甘氨酸代谢。
Amino Acids. 2018 Jan;50(1):11-27. doi: 10.1007/s00726-017-2508-0. Epub 2017 Nov 1.
8
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Nat Rev Gastroenterol Hepatol. 2018 Jan;15(1):11-20. doi: 10.1038/nrgastro.2017.109. Epub 2017 Sep 20.
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Lancet Diabetes Endocrinol. 2017 Dec;5(12):941-950. doi: 10.1016/S2213-8587(17)30313-3. Epub 2017 Sep 15.
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Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.非酒精性脂肪性肝病中氨基酸浓度的改变:肥胖和胰岛素抵抗的影响。
Hepatology. 2018 Jan;67(1):145-158. doi: 10.1002/hep.29465. Epub 2017 Nov 17.