Huang Sheau-Ling, Hsieh Ching-Lin, Wu Ruey-Meei, Lu Wen-Shian
School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan.
Division of Occupational Therapy, Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
PLoS One. 2017 Sep 25;12(9):e0184823. doi: 10.1371/journal.pone.0184823. eCollection 2017.
The Beck Depression Inventory II (BDI-II) and the Taiwan Geriatric Depression Scale (TGDS) are self-report scales used for assessing depression in patients with Parkinson's disease (PD) and geriatric people. The minimal detectable change (MDC) represents the least amount of change that indicates real difference (i.e., beyond random measurement error) for a single subject. Our aim was to investigate the test-retest reliability and MDC of the BDI-II and the TGDS in people with PD.
Seventy patients were recruited from special clinics for movement disorders at a medical center. The patients' mean age was 67.7 years, and 63.0% of the patients were male. All patients were assessed with the BDI-II and the TGDS twice, 2 weeks apart. We used the intraclass correlation coefficient (ICC) to determine the reliability between test and retest. We calculated the MDC based on standard error of measurement. The MDC% was calculated (i.e., by dividing the MDC by the possible maximal score of the measure).
The test-retest reliabilities of the BDI-II/TGDS were high (ICC = 0.86/0.89). The MDCs (MDC%s) of the BDI-II and TGDS were 8.7 (13.8%) and 5.4 points (18.0%), respectively. Both measures had acceptable to nearly excellent random measurement errors.
The test-retest reliabilities of the BDI-II and the TGDS are high. The MDCs of both measures are acceptable to nearly excellent in people with PD. These findings imply that the BDI-II and the TGDS are suitable for use in a research context and in clinical settings to detect real change in a single subject.
贝克抑郁量表第二版（BDI-II）和台湾老年抑郁量表（TGDS）是用于评估帕金森病（PD）患者和老年人抑郁状况的自评量表。最小可检测变化（MDC）代表单个受试者显示真实差异（即超出随机测量误差）所需的最小变化量。我们的目的是研究BDI-II和TGDS在PD患者中的重测信度和MDC。
从一家医疗中心的运动障碍专科门诊招募了70名患者。患者的平均年龄为67.7岁，63.0%为男性。所有患者均接受BDI-II和TGDS评估，两次评估间隔2周。我们使用组内相关系数（ICC）来确定重测之间的信度。我们根据测量标准误差计算MDC。计算MDC%（即MDC除以该测量可能的最高分）。
BDI-II/TGDS的重测信度较高（ICC = 0.86/0.89）。BDI-II和TGDS的MDC（MDC%）分别为8.7（13.8%）和5.4分（18.0%）。两种测量方法的随机测量误差均可接受至近乎完美。
BDI-II和TGDS的重测信度较高。在PD患者中，两种测量方法的MDC均可接受至近乎完美。这些发现表明，BDI-II和TGDS适用于研究环境和临床环境，以检测单个受试者的真实变化。
