Vermont Center on Behavior and Health, Burlington (Mr Middleton and Drs Ades and Gaalema); Departments of Psychiatry (Dr Gaalema) and Psychology (Mr Middleton and Dr Gaalema), University of Vermont, Burlington; and Division of Cardiology, University of Vermont College of Medicine, Burlington (Messrs Savage and Rengo and Drs Khadanga and Ades).
J Cardiopulm Rehabil Prev. 2022 May 1;42(3):163-171. doi: 10.1097/HCR.0000000000000657. Epub 2021 Nov 24.
Depression affects cardiac health and is important to track within cardiac rehabilitation (CR). Using two depression screeners within one sample, we calculated prevalence of baseline depressive symptomology, improvements during CR, and predictors of both.
Data were drawn from the University of Vermont Medical Center CR program prospectively collected database. A total of 1781 patients who attended between January 2011 and July 2019 were included. Two depression screeners (Geriatric Depression Scale-Short Form [GDS-SF] and Patient Health Questionnaire-9 [PHQ-9]) were compared on proportion of the sample categorized with ≥ mild or moderate levels of depressive symptoms (PHQ-9 ≥5, ≥10; GDS-SF ≥6, ≥10). Changes in depressive symptoms by screener were examined within patients who had completed ≥9 sessions of CR. Patient characteristics associated with depressive symptoms at entry, and changes in symptoms were identified.
Within those who completed ≥9 sessions of CR with exit scores on both screeners (n = 1201), entrance prevalence of ≥ mild and ≥ moderate depressive symptoms differed by screener (32% and 9% PHQ-9; 12% and 3% GDS-SF; both P< .001). Patients who were younger, female, with lower cardiorespiratory fitness (CRF) scores were more likely to have ≥ mild depressive symptoms at entry. Most patients with ≥ mild symptoms decreased severity by ≥1 category by exit (PHQ-9 = 73%; GDS-SF = 77%). Nonsurgical diagnosis and lower CRF were associated with less improvement in symptoms on the PHQ-9 (both P< .05).
Our results provide initial benchmarks of depressive symptoms in CR. They identify younger patients, women, patients with lower CRF, and those with nonsurgical diagnosis as higher risk groups for having depressive symptoms or lack of improvement in symptoms.
抑郁会影响心脏健康,因此在心脏康复(CR)中需要对其进行跟踪监测。本研究在同一研究样本中使用两种抑郁筛查工具,计算了基线时存在抑郁症状的比例、CR 期间的改善情况,以及两者的预测因素。
数据来自佛蒙特大学医学中心 CR 项目前瞻性收集的数据库。共纳入了 2011 年 1 月至 2019 年 7 月期间参加该项目的 1781 例患者。将两种抑郁筛查工具(老年抑郁量表简表[GDS-SF]和患者健康问卷-9[PHQ-9])进行比较,评估不同工具对样本中≥轻度或中度抑郁症状(PHQ-9≥5,≥10;GDS-SF≥6,≥10)的分类比例。对完成≥9 次 CR 治疗且有终点筛查得分的患者进行比较,观察两种筛查工具对抑郁症状的变化。确定了与入组时抑郁症状相关的患者特征,以及症状的变化情况。
在完成了≥9 次 CR 治疗且两种筛查工具都有终点得分的患者中(n=1201),不同筛查工具的入组时≥轻度和≥中度抑郁症状的比例不同(PHQ-9:32%和 9%;GDS-SF:12%和 3%;均 P<.001)。年龄较小、女性、心肺适能(CRF)评分较低的患者,入组时更可能存在≥轻度抑郁症状。大多数≥轻度症状的患者在终点时症状严重程度至少降低了一个类别(PHQ-9=73%;GDS-SF=77%)。非手术诊断和较低的 CRF 与 PHQ-9 症状改善程度较低相关(均 P<.05)。
本研究结果为 CR 中的抑郁症状提供了初步基准。结果显示,年龄较小、女性、CRF 较低的患者,以及非手术诊断的患者,为存在抑郁症状或症状无改善的高风险人群。