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[在宫颈癌活检样本中发现单纯疱疹病毒(HSV)样颗粒]

[Discovery of herpes simplex virus (HSV)-like particles in biopsy samples of cervical carcinoma].

作者信息

Chen M H

出版信息

Zhonghua Zhong Liu Za Zhi. 1985 Nov;7(6):430-1.

PMID:3015529
Abstract

The tissue of cervical cancer and HSV-2 infected baby rabbit kidney (BRK) cells were studied comparatively by electron microscope. In 2 out of 12 samples from patients with cervical carcinoma, some virus-like particles were observed in the cytoplasm or intercellular space. Some particles seemed to be enveloped by endoplasmic reticulum. According to their size, structure and morphology, these particles resembled the herpes simplex virus. The relationship between the discovery of herpes simplex virus-like particles in tissue of cervical cancer and the development of this cancer is discussed.

摘要

通过电子显微镜对宫颈癌组织和感染单纯疱疹病毒2型(HSV-2)的幼兔肾(BRK)细胞进行了比较研究。在12例宫颈癌患者的样本中,有2例在细胞质或细胞间隙中观察到一些病毒样颗粒。一些颗粒似乎被内质网包裹。根据其大小、结构和形态,这些颗粒类似于单纯疱疹病毒。本文讨论了在宫颈癌组织中发现单纯疱疹病毒样颗粒与该癌症发展之间的关系。

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