Kamalian L A, Makhmurian T D, Movsesian E A, Nadzharian N U, Gevorkian V I
Vopr Onkol. 1980;26(11):74-8.
Comparative studies of some properties of Herpes simplex viruses type I and II and their ability to reproduce latent infection in vitro revealed no essential differences between them. Virus-neutralizing and hemagglutinating antibodies to the virus type II are detected reliably more frequently in cervical cancer patients than in healthy ones. Forty six per cent of cervical cancer patients and thirty nine per cent of healthy females along with antibodies against the virus of serotype II showed a specific cellular response, which was demonstrated in the reaction of leucocyte migration inhibition. In patients with dissemination of the disease there is an inhibited cell immunity to Herpes virus without changing of the humoral resistance.
对I型和II型单纯疱疹病毒的某些特性及其在体外产生潜伏感染能力的比较研究表明,它们之间没有本质区别。与健康人相比,宫颈癌患者中能更频繁地可靠检测到针对II型病毒的病毒中和抗体和血凝抗体。46%的宫颈癌患者和39%的健康女性除了具有针对II型血清型病毒的抗体外,还表现出特异性细胞反应,这在白细胞迁移抑制反应中得到证实。在疾病播散的患者中,对疱疹病毒的细胞免疫受到抑制,而体液抵抗力没有改变。