Langerhans-Cell Histiocytosis.
作者信息
Allen Carl E, Merad Miriam, McClain Kenneth L
机构信息
From the Texas Children's Cancer Center and the Department of Pediatrics, Baylor College of Medicine, Houston (C.E.A., K.L.M.); and the Department of Oncological Sciences, the Precision Immunology Institute, and the Tisch Cancer Institute, Icahn School of Medicine, New York (M.M.).
出版信息
N Engl J Med. 2018 Aug 30;379(9):856-868. doi: 10.1056/NEJMra1607548.
Abstract
摘要
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本文引用的文献
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CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions.中枢神经系统朗格汉斯细胞组织细胞增生症：LCH 相关神经退行性变和肿块病变的常见造血起源。
Cancer. 2018 Jun 15;124(12):2607-2620. doi: 10.1002/cncr.31348. Epub 2018 Apr 6.
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Single-agent dabrafenib for -mutated histiocytosis.单药达拉非尼治疗 BRAF 突变型组织细胞增多症。 （你这里原文“-mutated”应该是有个具体基因名称没写全，我推测为BRAF ，你可根据实际情况调整）
Haematologica. 2018 Apr;103(4):e177-e180. doi: 10.3324/haematol.2017.185298. Epub 2018 Feb 22.
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RAF/MEK/extracellular signal-related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions.RAF/MEK/细胞外信号相关激酶通路抑制树突状细胞迁移，并将树突状细胞困在朗格汉斯细胞组织细胞增生症病变中。
J Exp Med. 2018 Jan 2;215(1):319-336. doi: 10.1084/jem.20161881. Epub 2017 Dec 20.
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JAMA Oncol. 2018 Mar 1;4(3):384-388. doi: 10.1001/jamaoncol.2017.5029.
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Evaluation and treatment of Langerhans cell histiocytosis patients with central nervous system abnormalities: Current views and new vistas.伴有中枢神经系统异常的朗格汉斯细胞组织细胞增多症患者的评估与治疗：当前观点与新展望
Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26784. Epub 2017 Sep 25.
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A genome-wide association study of LCH identifies a variant in associated with susceptibility.一项关于朗格汉斯细胞组织细胞增生症（LCH）的全基因组关联研究确定了一个与之相关的易感性变异。
Blood. 2017 Nov 16;130(20):2229-2232. doi: 10.1182/blood-2017-08-800565. Epub 2017 Sep 21.
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A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.红系髓系祖细胞中的体细胞突变会引发神经退行性疾病。
Nature. 2017 Sep 21;549(7672):389-393. doi: 10.1038/nature23672. Epub 2017 Aug 30.
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New somatic BRAF splicing mutation in Langerhans cell histiocytosis.朗格汉斯细胞组织细胞增生症中的新体细胞 BRAF 剪接突变。
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Targeted therapies in 54 patients with Erdheim-Chester disease, including follow-up after interruption (the LOVE study).针对54例 Erdheim-Chester病患者的靶向治疗，包括中断治疗后的随访（LOVE研究）。
Blood. 2017 Sep 14;130(11):1377-1380. doi: 10.1182/blood-2017-03-771873. Epub 2017 Jun 30.
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Circulating cell-free BRAF as a biomarker in children with Langerhans cell histiocytosis.循环无细胞 BRAF 作为朗格汉斯细胞组织细胞增生症患儿的生物标志物。
Br J Haematol. 2017 Aug;178(3):457-467. doi: 10.1111/bjh.14695. Epub 2017 Apr 25.
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