Horm Res Paediatr. 2018;90(2):73-81. doi: 10.1159/000492129. Epub 2018 Aug 29.
This review focuses on the current knowledge of the effects of thyroid hormones on central nervous system differentiation and development in animals and the human fetal brain. The outcomes of children with congenital hypothyroidism and of newborns with hypothyroid pregnant mothers are emphasized, focusing on how therapies could affect and especially improve the outcomes.
这篇综述重点介绍了甲状腺激素对动物中枢神经系统分化和发育以及人类胎儿大脑的影响的现有知识。强调了先天性甲状腺功能减退症儿童和患有甲状腺功能减退症孕妇的新生儿的结局,并重点讨论了治疗方法如何影响(尤其是改善)这些结局。