Marx A, Rüdiger T, Rößner E, Tzankov A, de Montpréville V T, Rieker R R, Ströbel P, Weis C-A
Pathologisches Institut, Universitätsmedizin Mannheim, Universität Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.
Pathologisches Institut, Klinikum Karlsruhe, Karlsruhe, Deutschland.
Pathologe. 2018 Sep;39(5):390-397. doi: 10.1007/s00292-018-0485-z.
Ectopic thymic tissue outside its core position in the antero-superior mediastinum is quite common owing to the complexity of embryonal thymus development, whereby reported prevalence values (1 to 90%) are heavily dependent on the method of investigation and the intensity of the workup. The debated prevalence and relevance of ectopic thymic tissue and its accessibility underlie the ongoing discussion whether modern, minimally invasive thymectomy strategies can match the proven benefit of the radical transsternal thymectomy procedure for the treatment of Myasthenia gravis. In this context, the following article covers the etiology, prevalence, and location of normal-looking, reactive, and neoplastic ectopic thymic tissue. Furthermore, ectopic tissues and tumors inside or adjacent to the thymus are mentioned.
由于胚胎期胸腺发育的复杂性，位于前上纵隔核心位置之外的异位胸腺组织相当常见，因此报告的患病率值（1%至90%）在很大程度上取决于调查方法和检查的强度。异位胸腺组织的患病率及其相关性存在争议，且其可及性是目前关于现代微创胸腺切除术策略能否与经胸骨根治性胸腺切除术治疗重症肌无力已证实的益处相匹配的讨论基础。在此背景下，以下文章涵盖了外观正常、反应性和肿瘤性异位胸腺组织的病因、患病率和位置。此外，还提到了胸腺内部或附近的异位组织和肿瘤。
