Thomas Geraldine
Department of Surgery and Cancer, Imperial College London, Charing Cross Hospital, Fulham Palace Road, London, UK.
Radiat Prot Dosimetry. 2018 Dec 1;182(1):53-57. doi: 10.1093/rpd/ncy146.
It has long been known that the thyroid is a radiosensitive organ. It is the only organ in the body to both take up and bind iodine, and therefore exposure to radioiodine in fallout from nuclear power plants poses an increased danger to the thyroid. Studies following the Chernobyl accident have shown that children are most at risk from the development of thyroid cancer following exposure to radioactive iodine in fallout. This article reviews what we know so far about the type of thyroid cancer induced by radiation, its molecular biology and clinical outcome.
长期以来，人们都知道甲状腺是一个对辐射敏感的器官。它是人体中唯一摄取并结合碘的器官，因此，接触核电站沉降物中的放射性碘会给甲状腺带来更大的危险。切尔诺贝利事故后的研究表明，儿童在接触沉降物中的放射性碘后患甲状腺癌的风险最高。本文综述了我们目前对辐射诱发的甲状腺癌类型、其分子生物学及临床结果的了解。
