Singhal Rameshwari, Agarwal Vivek, Rastogi Pavitra, Khanna Richa, Tripathi Shuchi
Department of Periodontology, Faculty of Dental Sciences, King George's Medical University, Lucknow, UP, India.
Department of Medicine, Mayo Institute of Medical Sciences, Barabanki, UP, India.
Saudi Dent J. 2018 Jan;30(1):53-62. doi: 10.1016/j.sdentj.2017.10.006. Epub 2017 Nov 3.
The aim of the present study was to explore the adjunctive use of Acacia arabica gel in the treatment of chronic periodontitis.
Single centre, randomised, triple blind, controlled trial on mild to moderate chronic periodontitis patients; Group I (SRP + Acacia arabica, n = 40) and Group II (SRP + placebo, n = 40); were analysed for clinical improvements in periodontal pocket depth (PPD) and clinical attachment levels (CAL) at baseline, 15 and 90 days on application of gels. Gingival index and plaque index were assessed as secondary parameters.
Statistically significant PPD reduction (p < .05) and CAL gain (p < .05) was observed with use of Acacia arabica gel. The reduction in sites with moderate PPD was observed more among Group I than Group II and the difference was statistically significant (p = .001). Secondary outcome variables; Plaque Index and Gingival Index showed better resolution with Acacia arabica gel.
Acacia arabica leads to better clinical outcomes in patients with mild to moderate chronic periodontitis with effective antiplaque and anti-gingivitis action. It may be recommended adjunct to SRP for maintenance in patients with mild to moderate chronic periodontitis.
本研究旨在探讨阿拉伯胶凝胶在慢性牙周炎治疗中的辅助应用。
对轻至中度慢性牙周炎患者进行单中心、随机、三盲对照试验；将患者分为两组，第一组（龈下刮治术+阿拉伯胶，n = 40）和第二组（龈下刮治术+安慰剂，n = 40）；在应用凝胶后的基线、15天和90天分析牙周袋深度（PPD）和临床附着水平（CAL）的临床改善情况。牙龈指数和菌斑指数作为次要参数进行评估。
使用阿拉伯胶凝胶后观察到PPD有统计学意义的降低（p < 0.05）和CAL增加（p < 0.05）。第一组中中度PPD部位的减少比第二组更明显，差异有统计学意义（p = 0.001）。次要结局变量；菌斑指数和牙龈指数在使用阿拉伯胶凝胶后显示出更好的改善。
阿拉伯胶对轻至中度慢性牙周炎患者具有更好的临床疗效，具有有效的抗菌斑和抗牙龈炎作用。对于轻至中度慢性牙周炎患者，推荐将其作为龈下刮治术的辅助治疗用于维持治疗。
