J Orthop Sports Phys Ther. 2018 Sep;48(9):730-731. doi: 10.2519/jospt.2018.0704.
Clinicians might think researchers are obsessed with randomized controlled trials (RCTs). But why is that? Randomization enables us to make some specific conclusions that are not possible in other study designs. This is not to say that any study that is randomized automatically gives us the correct answer to the question; there are other aspects of study quality that need to be considered. One of these is sample size: the advantages of randomization only really hold true if there are enough people in the study. However, it's probably not too much to say that randomization is the most important study design feature for treatment-comparison studies. J Orthop Sports Phys Ther 2018;48(9):730-731. doi:10.2519/jospt.2018.0704.
临床医生可能认为研究人员对随机对照试验(RCT)过于痴迷。但为什么会这样呢?随机化使我们能够得出一些在其他研究设计中不可能得出的具体结论。这并不是说任何随机化的研究都能自动为我们提供问题的正确答案;还需要考虑研究质量的其他方面。其中之一是样本量:只有在研究中有足够多的人时,随机化的优势才真正成立。然而,我们可以毫不夸张地说,随机化是治疗比较研究中最重要的研究设计特征。J Orthop Sports Phys Ther 2018;48(9):730-731.doi:10.2519/jospt.2018.0704.