Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Pediatrix Medical Group, Sunrise, FL.
J Pediatr. 2018 Nov;202:23-30.e1. doi: 10.1016/j.jpeds.2018.07.001. Epub 2018 Aug 28.
To identify factors associated with prolonged maternal breast milk (BM) provision in very low birth weight (VLBW) infants.
This was a cohort study of VLBW infants who initially received maternal BM and were born at one of 197 neonatal intensive care units managed by the Pediatrix Medical Group from 2010 to 2012. We used multivariable logistic regression to identify demographic, clinical, and maternal factors associated with provision of maternal BM on day of life (DOL) 30 and at discharge.
Median gestational age for all infants was 28 weeks (25, 75 percentiles: 26, 30), and median maternal age was 28 years (23, 33). Of 8806 infants, 6261 (71%) received maternal BM on DOL 30, and 4003 of 8097 (49%) received maternal BM at discharge to home. Predictors of maternal BM provision at DOL 30 included increased maternal age, white maternal race, absence of history of necrotizing enterocolitis or late-onset sepsis, higher household income, lower education level, lack of donor BM exposure, and lower gestational age.
Our results suggest that maternal-infant demographic and clinical factors and household neighborhood socioeconomic characteristics were associated with provision of maternal BM at 30 postnatal days to VLBW infants. Identification of these factors allows providers to anticipate mothers' needs and develop tailored interventions designed to improve rates of prolonged maternal BM provision and infant outcomes.
确定与极低出生体重(VLBW)婴儿延长母乳喂养相关的因素。
这是一项队列研究,纳入了 2010 年至 2012 年期间,由佩特里克斯医疗集团管理的 197 个新生儿重症监护病房中最初接受母乳喂养的 VLBW 婴儿。我们使用多变量逻辑回归分析,确定与第 30 天和出院时提供母乳喂养相关的人口统计学、临床和产妇因素。
所有婴儿的中位胎龄为 28 周(25,75%分位数:26,30),中位产妇年龄为 28 岁(23,33)。在 8806 名婴儿中,6261 名(71%)在第 30 天接受了母乳喂养,8097 名中的 4003 名(49%)在出院回家时接受了母乳喂养。第 30 天提供母乳喂养的预测因素包括产妇年龄增加、白人产妇种族、无坏死性小肠结肠炎或晚发性败血症病史、家庭收入较高、教育水平较低、无供体 BM 暴露和较低的胎龄。
我们的结果表明,产妇-婴儿的人口统计学和临床因素以及家庭社区的社会经济特征与 VLBW 婴儿在 30 天内提供母乳喂养相关。确定这些因素可以让提供者预测母亲的需求,并制定有针对性的干预措施,以提高延长母乳喂养的比例和婴儿的结局。