Division of General Internal Medicine and Geriatrics, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States; Center for Primary Care Innovation, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
Contemp Clin Trials. 2018 Oct;73:92-97. doi: 10.1016/j.cct.2018.08.013. Epub 2018 Aug 29.
Hypertension is a major cause of morbidity and mortality but frequently remains uncontrolled. A smartphone application that provides coaching regarding home blood pressure monitoring and other aspects of hypertension self-care and related behavior change may be a scalable way to help manage hypertension.
METHODS/DESIGN: The Smart Hypertension Control Study is a prospective, randomized controlled trial to assess the effects of a hypertension personal control program (HPCP), which consists of an automated artificial intelligence smartphone application that provides individualized support and coaching to promote home monitoring and healthy behavior changes related to hypertension self-management. Enrolled adults with uncontrolled hypertension will be randomized in a 1:1 fashion to the HPCP with home blood pressure monitoring or to home monitoring alone. We plan to enroll 350 participants, with a target of 300 participants with complete six-month follow-up data. The primary study outcome will be systolic blood pressure at six months. Additional outcomes include measures of antihypertensive medication adherence, home blood pressure monitoring practices, self-management practices, weight, and self-reported health behaviors.
The Smart Hypertension Control Study will evaluate blood pressure and hypertension self-management behavior outcomes in participants with uncontrolled hypertension exposed to a smartphone-based hypertension health coaching application in addition to home blood pressure monitoring compared to those exposed to home blood pressure monitoring alone.
高血压是导致发病率和死亡率的主要原因，但往往仍未得到控制。一款提供家庭血压监测和高血压自我护理以及相关行为改变方面指导的智能手机应用程序，可能是帮助管理高血压的一种可扩展的方法。
方法/设计：智能高血压控制研究是一项前瞻性、随机对照试验，旨在评估高血压个人控制计划（HPCP）的效果，该计划由一个自动化人工智能智能手机应用程序组成，为促进家庭监测和与高血压自我管理相关的健康行为改变提供个性化支持和指导。未得到控制的高血压成年患者将以 1:1 的比例随机分配到 HPCP 加家庭血压监测组或仅家庭监测组。我们计划招募 350 名参与者，目标是有 300 名参与者完成为期六个月的完整随访数据。主要研究结果将是六个月时的收缩压。其他结果包括抗高血压药物依从性、家庭血压监测实践、自我管理实践、体重和自我报告的健康行为的测量。
智能高血压控制研究将评估暴露于基于智能手机的高血压健康指导应用程序加家庭血压监测的未控制高血压患者的血压和高血压自我管理行为结果，与仅暴露于家庭血压监测的患者相比。
