Universidade federal do piauí, Bairro ininga, Teresina, PI CEP 64049-550, Brazil.
Universidade federal do piauí, Bairro ininga, Teresina, PI CEP 64049-550, Brazil.
Intensive Crit Care Nurs. 2018 Dec;49:51-57. doi: 10.1016/j.iccn.2018.08.003. Epub 2018 Aug 29.
To evaluate the colonisation rate of Staphylococcus aureus in the oropharynx and the insertion site of central venous catheters in intensive care unit patients.
Cross-sectional study.
Brazilian intensive care unit.
Samples were collected from October to December 2015 from the oropharyngeal cavity and central venous catheter insertion site of 110 patients. Samples that presented growth of Staphylococcus aureus were isolated and their sensitivity profiles were tested for several antimicrobials.
The study participants (110) were mostly females older than 60 years (53.6%). The mean length of hospitalisation was 15.5 days (±31.3). A total of 188 biological samples were collected: 110 collected from the oropharynx and 78 from the central venous catheter insertion site. A 35% (n = 38/110) S. aureus colonisation rate of the patients was observed in at least one collection site. In the oropharynx alone, a 31% rate (n = 34/110) was found, and a 12.8% rate (n = 10/78) at central venous catheter insertion sites only. MRSA colonisation in the oropharynx or at the central venous catheter occurred in 29 (26.4%) patients and vancomycin resistant Staphylococcus aureus was present in 24 (22.4%) of the patients studied. Patients hospitalised for seven days or more were 4.8 times more likely to be colonised compared to patients hospitalised less than seven days (95% CI = 1.2-28.5).
The oropharynx and the central venous catheter are important reservoirs of this bacterium that in critical conditions may become pathogenic. The data showed a high degree of resistance of the bacterial populations isolated to different drugs, which may hinder the control of these organisms.
评估重症监护病房患者口咽部和中心静脉导管置管部位金黄色葡萄球菌定植率。
横断面研究。
巴西重症监护病房。
2015 年 10 月至 12 月，从 110 例患者的口咽部和中心静脉导管置管部位采集标本。对出现金黄色葡萄球菌生长的标本进行分离，并检测其对几种抗菌药物的药敏谱。
研究对象（110 例）均为年龄＞60 岁的女性（53.6%），平均住院时间为 15.5 天（±31.3）。共采集 188 份生物标本：110 份来自口咽部，78 份来自中心静脉导管置管部位。至少有一个采集部位发现 35%（n=38/110）的患者存在金黄色葡萄球菌定植。单纯口咽部的定植率为 31%（n=34/110），单纯中心静脉导管置管部位的定植率为 12.8%（n=10/78）。口咽部或中心静脉导管处发生耐甲氧西林金黄色葡萄球菌定植的患者为 29 例（26.4%），万古霉素耐药金黄色葡萄球菌定植的患者为 24 例（22.4%）。住院 7 天或以上的患者定植的可能性是住院＜7 天患者的 4.8 倍（95%CI=1.2-28.5）。
口咽部和中心静脉导管是该细菌的重要储库，在危重症情况下可能成为病原菌。数据显示，分离的细菌种群对不同药物的耐药程度较高，这可能会阻碍这些病原体的控制。
