组织细胞增多症X；43例随访
Histiocytosis X; follow-up of 43 cases.
作者信息
Sims D G
出版信息
Arch Dis Child. 1977 Jun;52(6):433-40. doi: 10.1136/adc.52.6.433.
Abstract
Over a 29-year period, 43 cases of histiocytosis X presented in children under the age of 12 years. 29 patients (67%) have survived, and of these, 15 (52%) have a detectable disability. It was confirmed that young age at presentation and evidence of soft tissue involvement were associated with a worse prognosis. The majority of deaths were associated with pulmonary involvement. 14 patients developed diabetes insipidus. 5 of the surviving adults have heights below the 3rd centile. Puberty usually occurred at a normal age. Follow-up studies on 12 survivors showed no evidence of residual abnormality of haematology, deficient lymphocyte function, or yeast opsonization. HLA typing showed no unusual pattern. Mild carbon monoxide diffusion deffects were present in 4 patients and other abnormalities were detected on lung function tests.
摘要
在29年期间，43例朗格汉斯细胞组织细胞增多症出现在12岁以下儿童中。29名患者（67%）存活，其中15名（52%）有可检测到的残疾。已证实发病时年龄小和软组织受累证据与预后较差有关。大多数死亡与肺部受累有关。14名患者发生尿崩症。5名存活的成年人身高低于第3百分位数。青春期通常在正常年龄出现。对12名幸存者的随访研究未发现血液学残留异常、淋巴细胞功能缺陷或酵母调理作用的证据。HLA分型未显示异常模式。4名患者存在轻度一氧化碳弥散缺陷，肺功能测试检测到其他异常。
相似文献
1
Histiocytosis X; follow-up of 43 cases.组织细胞增多症X；43例随访
Arch Dis Child. 1977 Jun;52(6):433-40. doi: 10.1136/adc.52.6.433.
2
Disseminated histiocytosis X: analysis of prognostic factors based on a retrospective study of 50 cases.播散性组织细胞增多症X：基于50例回顾性研究的预后因素分析
Cancer. 1979 Nov;44(5):1824-38. doi: 10.1002/1097-0142(197911)44:5<1824::aid-cncr2820440542>3.0.co;2-j.
3
Skeletal Langerhans cell histiocytosis in children: permanent consequences and health-related quality of life in long-term survivors.儿童骨骼朗格汉斯细胞组织细胞增多症：长期存活者的永久性后果及与健康相关的生活质量
Pediatr Blood Cancer. 2008 Mar;50(3):607-12. doi: 10.1002/pbc.21322.
4
A multicentre retrospective survey of Langerhans' cell histiocytosis: 348 cases observed between 1983 and 1993. The French Langerhans' Cell Histiocytosis Study Group.朗格汉斯细胞组织细胞增多症的多中心回顾性调查：1983年至1993年间观察的348例病例。法国朗格汉斯细胞组织细胞增多症研究小组。
Arch Dis Child. 1996 Jul;75(1):17-24. doi: 10.1136/adc.75.1.17.
5
The frequency and natural history of diabetes insipidus in children with Langerhans-cell histiocytosis.
N Engl J Med. 1989 Oct 26;321(17):1157-62. doi: 10.1056/NEJM198910263211704.
6
Diabetes insipidus in Langerhans cell histiocytosis: When is treatment indicated?朗格汉斯细胞组织细胞增多症中的尿崩症：何时需要治疗？
Pediatr Blood Cancer. 2009 May;52(5):555-6. doi: 10.1002/pbc.21924.
7
Langerhans cell histiocytosis: 23 years' paediatric experience highlights severe long-term sequelae.朗格汉斯细胞组织细胞增多症：23年的儿科经验凸显了严重的长期后遗症。
Scott Med J. 2014 Aug;59(3):149-57. doi: 10.1177/0036933014542387. Epub 2014 Jul 3.
8
Langerhans cell histiocytosis of the orbit.眼眶朗格汉斯细胞组织细胞增多症
Eur J Ophthalmol. 2013 Jul-Aug;23(4):578-83. doi: 10.5301/ejo.5000244. Epub 2013 Mar 6.
9
Histiocytosis-X in Saudi children.沙特儿童的组织细胞增多症-X
Indian J Cancer. 1991 Jun;28(2):53-60.
10
Craniospinal Langerhans cell histiocytosis in children: 30 years' experience at a single institution.儿童颅脊髓朗格汉斯细胞组织细胞增多症：单一机构30年的经验
J Neurosurg Pediatr. 2008 Mar;1(3):187-95. doi: 10.3171/PED/2008/1/3/187.
引用本文的文献
1
Rare Diseases of the Middle Ear and Lateral Skull Base.中耳及侧颅底罕见病
Laryngorhinootologie. 2021 Apr;100(S 01):S1-S30. doi: 10.1055/a-1347-4171. Epub 2021 Apr 30.
2
Langerhans cell histiocytosis with presentation as orbital disease.以眼眶疾病为表现的朗格汉斯细胞组织细胞增多症。
J Pediatr Neurosci. 2015 Apr-Jun;10(2):162-5. doi: 10.4103/1817-1745.159197.
3
Histiocytosis-X of fronto-ethmoid region.额筛区域的组织细胞增多症-X
Indian J Otolaryngol Head Neck Surg. 1997 Jan;49(1):41-3. doi: 10.1007/BF02991710.
4
Orbital manifestations of Langerhans Cell Histiocytosis: A report of three cases.朗格汉斯细胞组织细胞增多症的眼眶表现：三例报告
Oman J Ophthalmol. 2009 Sep;2(3):137-40. doi: 10.4103/0974-620X.57315.
5
Hypopituitarism in langerhans cell histiocytosis: seven cases and literature review.朗格汉斯细胞组织细胞增多症中的垂体功能减退：7例病例及文献综述
J Endocrinol Invest. 2001 Sep;24(8):612-7. doi: 10.1007/BF03343902.
6
Endocrinological aspects of Langerhans cell histiocytosis complicated with diabetes insipidus.朗格汉斯细胞组织细胞增多症合并尿崩症的内分泌学方面
J Endocrinol Invest. 1998 Jul-Aug;21(7):428-33. doi: 10.1007/BF03347321.
7
Growth hormone replacement in patients with Langerhan's cell histiocytosis.朗格汉斯细胞组织细胞增多症患者的生长激素替代治疗
Arch Dis Child. 1998 May;78(5):469-73. doi: 10.1136/adc.78.5.469.
8
A multicentre retrospective survey of Langerhans' cell histiocytosis: 348 cases observed between 1983 and 1993. The French Langerhans' Cell Histiocytosis Study Group.朗格汉斯细胞组织细胞增多症的多中心回顾性调查：1983年至1993年间观察的348例病例。法国朗格汉斯细胞组织细胞增多症研究小组。
Arch Dis Child. 1996 Jul;75(1):17-24. doi: 10.1136/adc.75.1.17.
9
Diabetes insipidus for five years preceding the diagnosis of hypothalamic Langerhans cell histiocytosis.
J Endocrinol Invest. 1995 Sep;18(8):663-6. doi: 10.1007/BF03349786.
10
Langerhans cell histiocytosis--clinical and epidemiological aspects.朗格汉斯细胞组织细胞增多症——临床与流行病学方面
Br J Cancer Suppl. 1994 Sep;23:S11-6.
本文引用的文献
1
EOSINOPHILIC GRANULOMA AND ITS VARIANTS WITH SPECIAL REFERENCE TO LUNG INVOLVEMENT. A REPORT OF 12 PATIENTS.
Q J Med. 1964 Jul;33:337-59.
2
3
4
Acute disseminated histiocytosis X: a case with transition from eosinophilic granuloma of bone to Letterer-Siwe disease.
Australas Ann Med. 1969 May;18(2):135-7. doi: 10.1111/imj.1969.18.2.135.
5
Pulmonary manifestations of histiocytosis X.组织细胞增多症X的肺部表现。
Proc R Soc Med. 1971 Apr;64(4):338-40. doi: 10.1177/003591577106400404.
6
Histiocytosis X.组织细胞增多症X
J Bone Joint Surg Br. 1971 Aug;53(3):366-82.
7
Histiocytic reaction in dysgammaglobulinemia and congenital rubella.
Pediatrics. 1970 Jul;46(1):89-96.
8
Histiocytic reticulosis. A review of 20 patients in the paediatric age range.组织细胞性网状细胞增多症。对20例儿童期患者的回顾。
Med J Aust. 1969 Sep 6;2(10):485-8.
9
Histiocytosis: a histologic classification with clinical correlation.组织细胞增多症：一种具有临床相关性的组织学分类。
Perspect Pediatr Pathol. 1973;1:251-83.
10
Immunologic parameters in histocytosis-X.组织细胞增多症-X中的免疫学参数。
Cancer. 1973 Oct;32(4):796-802. doi: 10.1002/1097-0142(197310)32:4<796::aid-cncr2820320409>3.0.co;2-o.
Zotero 插件