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日常生活活动障碍与中年及以上中国成年人及其配偶抑郁症状的关系:一项基于社区的研究。

Association between activities of daily living disability and depression symptoms of middle-aged and older Chinese adults and their spouses: A community based study.

机构信息

Department of Social Medicine and Health Management, School of Public Health, Jilin University, Changchun, China.

Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, China.

出版信息

J Affect Disord. 2019 Jan 1;242:135-142. doi: 10.1016/j.jad.2018.08.060. Epub 2018 Aug 16.

DOI:10.1016/j.jad.2018.08.060
PMID:30173061
Abstract

BACKGROUND

Little is known about the impact of activities of daily living (ADL) disability on personal and spouse depression symptoms among Chinese.

METHODS

We used data from the baseline and 2013 follow-up surveys of the China Health and Retirement Longitudinal Study, a nationally representative survey in 17,708 adults aged 45 years and older, to evaluate cross-sectional and prospective association between ADL disability and depression symptoms of subjects and their spouses. The derived basic ADL scale (BADL) and the Center for Epidemiologic Studies Depression Scale short form were utilized to assess ADL disability and depressive symptoms, respectively. Logistic regression was used to calculate odds ratio (OR) and 95% confidence interval (CI), adjusting for depression risk factors and taking into account the complex survey design and response rate.

RESULTS

There were 15,890 subjects included in the study. Prevalence of baseline depression symptoms was 29.5% (95%CI 27.9-31.1%), 58.0% (95%CI 54.5-61.4%) and 73.6% (95%CI 70.4-76.8%) in subjects with BADL scores of 0, 1 and ≥2, respectively, and 27.0% (95%CI 25.3-28.7%), 34.2% (95%CI 30.0-38.4%) and 43.8% (95%CI 39.1-48.5%) in subjects without ADL disability while having spouses with BADL scores of 0, 1 and ≥2, respectively. Prospectively, BADL score ≥2 was associated with higher risk of depression symptoms of subjects (OR 1.63, 95% CI 1.03-2.57) and their spouses (OR 1.50, 95% CI 1.01-2.22).

LIMITATIONS

Bias might be introduced because of observational study design, and findings may not be generalizable to younger population.

CONCLUSIONS

ADL disability might have potential to increase risk of depression symptoms of middle-aged and older Chinese adults and their spouses.

摘要

背景

对于日常生活活动(ADL)障碍对中国人群中个体和配偶抑郁症状的影响知之甚少。

方法

我们使用了中国健康与退休纵向研究基线和 2013 年随访调查的数据,该研究是一项针对 17708 名 45 岁及以上成年人的全国代表性调查,以评估 ADL 障碍与研究对象及其配偶抑郁症状的横断面和前瞻性关联。采用基本日常生活活动量表(BADL)和流行病学研究抑郁量表短表来评估 ADL 障碍和抑郁症状。采用 logistic 回归计算比值比(OR)和 95%置信区间(CI),调整抑郁风险因素,并考虑到复杂的调查设计和应答率。

结果

共纳入 15890 名研究对象。基线时抑郁症状的患病率分别为 BADL 评分为 0、1 和≥2 的研究对象中为 29.5%(95%CI 27.9-31.1%)、58.0%(95%CI 54.5-61.4%)和 73.6%(95%CI 70.4-76.8%),无 ADL 障碍且配偶 BADL 评分为 0、1 和≥2 的研究对象中为 27.0%(95%CI 25.3-28.7%)、34.2%(95%CI 30.0-38.4%)和 43.8%(95%CI 39.1-48.5%)。前瞻性分析显示,BADL 评分≥2 与研究对象(OR 1.63,95%CI 1.03-2.57)和其配偶(OR 1.50,95%CI 1.01-2.22)发生抑郁症状的风险增加相关。

局限性

由于观察性研究设计可能存在偏倚,研究结果可能不适用于年轻人群。

结论

ADL 障碍可能会增加中国中老年人及其配偶发生抑郁症状的风险。

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