抗体介导的抗鸭肠炎病毒感染作用。
Antibody-mediated resistance against duck enteritis virus infection.
作者信息
Lam K M, Lin W Q
出版信息
Can J Vet Res. 1986 Jul;50(3):380-3.
Vaccination of ducks with an apathogenic strain of duck enteritis virus resulted in protection against challenge with the virulent Lake Andes strain of duck enteritis virus by intramuscular inoculation or contact exposure. Antisera produced in the vaccinated ducks were able to transfer resistance against the challenge strain to recipient ducks. Antisera against duck enteritis virus were cytotoxic for duck enteritis virus-infected duck embryo fibroblasts in the presence of guinea pig complement. These in vivo and in vitro data suggest that the humoral immune mechanism plays a role in protecting ducks from duck enteritis virus infection.
用鸭肠炎病毒无毒株对鸭进行疫苗接种，通过肌肉注射或接触暴露，可使其免受鸭肠炎病毒强毒株安第斯湖株的攻击。接种疫苗的鸭产生的抗血清能够将对攻击毒株的抵抗力转移给受体鸭。在豚鼠补体存在的情况下，抗鸭肠炎病毒抗血清对感染鸭肠炎病毒的鸭胚成纤维细胞具有细胞毒性。这些体内和体外数据表明，体液免疫机制在保护鸭免受鸭肠炎病毒感染中发挥作用。
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