Sahan Selda, Demirbilek Yasemin, Sonmez Cemile, Temel Fehminaz, Sencan Irfan
Department of Health Threats Early Warning and Response, General Directorate of Public Health.
Department of Microbiology Reference Laboratories and Biological Products, General Directorate of Public Health.
Jpn J Infect Dis. 2019 Jan 23;72(1):14-18. doi: 10.7883/yoken.JJID.2018.222. Epub 2018 Aug 31.
The aim of this study was to determine the seropositivity levels of tetanus vaccine by age group in Ankara province, identify possible factors that affect immune status, and develop public health recommendations, especially for those 50 years and older. This cross-sectional epidemiological study covered individuals aged 3 years and older who are registered in the Family Medicine Information System. We received blood samples from 992 individuals and included 968 surveys in the analysis. Protective tetanus antibody levels were 80.5% in the 3-5 years age group, 92.0% in the 6-12 years age group, 94.3% in the 13-20 years age group, 95.2% in the 21-39 years age group, 84.4% in the 40-49 years age group, and 57.3% in the 50 years and older age group. Tetanus seropositivity decreased with age. Awareness of the importance of tetanus vaccine boosters for adults should be increased by providing training, ensuring booster vaccination against tetanus at 10-year intervals, and if necessary, considering mandatory tetanus vaccination for those 50 years and older.
本研究的目的是确定安卡拉省各年龄组破伤风疫苗的血清阳性水平,识别影响免疫状态的可能因素,并制定公共卫生建议,特别是针对50岁及以上人群。这项横断面流行病学研究涵盖了在家庭医学信息系统中登记的3岁及以上个体。我们从992名个体中采集了血样,并将968份调查问卷纳入分析。3至5岁年龄组的破伤风保护性抗体水平为80.5%,6至12岁年龄组为92.0%,13至20岁年龄组为94.3%,21至39岁年龄组为95.2%,40至49岁年龄组为84.4%,50岁及以上年龄组为57.3%。破伤风血清阳性率随年龄增长而下降。应通过提供培训、确保每10年进行一次破伤风加强免疫接种,以及在必要时考虑对50岁及以上人群进行强制性破伤风疫苗接种,来提高成年人对破伤风疫苗加强针重要性的认识。