Vivas-Rosales Irving Jesús, Hernández-Ojeda Mariana, O'Farrill-Romanillos Patricia María, Herrera-Sánchez Diana Andrea, Maciel-Fierro Abril Elena, Núñez-Enríquez Juan Carlos
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Ciudad de México, México.
Rev Alerg Mex. 2018 Jul-Sep;65(3):242-249. doi: 10.29262/ram.v65i3.399.
Common variable immunodeficiency (CVID) is the most common primary symptomatic humoral immunodeficiency in adults. Antibody deficiency entails higher susceptibility to sinopulmonary infections and bronchiectasis formation, which is related to increased mortality. Scales have been established to assess the degree of severity of bronchiectasis in order to predict outcomes such as mortality, exacerbations and hospitalizations.
To determine bronchiectasis severity in adult patients with common variable immunodeficiency using the Brief Symptom Inventory scale.
Cross-sectional study in adult population diagnosed with common variable immunodeficiency and attended to at the Mexican Institute of Social Security National Medical Center Siglo XXI Specialty Hospital.
Bronchiectasis severity according to the Brief Symptom Inventory was mild in 60% of patients and moderate in 40%. Statistically significant differences were found for body mass index, number of affected lobes and type of bronchiectasis (p < 0.001).
Using bronchiectasis severity scales in patients with common variable immunodeficiency is indispensable for clinical and therapeutic decision making; however, determining the most appropriate instrument to assess bronchiectasis severity in this population is necessary.
普通变异型免疫缺陷（CVID）是成人中最常见的原发性症状性体液免疫缺陷。抗体缺乏会导致对鼻窦肺部感染和支气管扩张形成的易感性增加，这与死亡率升高有关。已经建立了评估支气管扩张严重程度的量表，以预测死亡率、病情加重和住院等结果。
使用简明症状量表确定成人普通变异型免疫缺陷患者的支气管扩张严重程度。
对在墨西哥社会保障局国立医学中心西格洛 XXI 专科医院就诊的诊断为普通变异型免疫缺陷的成年人群进行横断面研究。
根据简明症状量表，60%的患者支气管扩张严重程度为轻度，40%为中度。在体重指数、受累肺叶数量和支气管扩张类型方面发现了统计学上的显著差异（p < 0.001）。
在普通变异型免疫缺陷患者中使用支气管扩张严重程度量表对于临床和治疗决策是必不可少的；然而，确定评估该人群支气管扩张严重程度的最合适工具是必要的。
