Department of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China (mainland).
Med Sci Monit. 2018 Sep 4;24:6151-6156. doi: 10.12659/MSM.908146.
BACKGROUND We explored the intervention effect of a smartphone medical app on complications and quality of life of patients with nasopharyngeal carcinoma who underwent radiotherapy and chemotherapy. MATERIAL AND METHODS We divided 132 patients with nasopharyngeal carcinoma who received radiotherapy and chemotherapy for the first time, in accordance with the random number table method, into a control group (67 patients) and an intervention group (65 patients). Patients in control group were discharged with standard care and patients in the intervention group used a smartphone medical app after discharge. Data on adverse effects of radiotherapy and chemotherapy, complications, and quality of life were collected and analyzed. RESULTS There was no difference between the complications of radiotherapy and chemotherapy and quality of life between the 2 groups at discharge (P>0.05). The incidence of oral mucositis, xerostomia, mouth-opening difficulties, and nasal congestion in the intervention group was significantly lower than in the control group at 6 months after discharge and quality of life was significantly higher than in the control group (P<0.05). CONCLUSIONS Reasonable use of this smartphone app can improve the exercise compliance of discharged patients with nasopharyngeal carcinoma who underwent radiotherapy and chemotherapy, reduce the adverse reactions and complications of radiotherapy and chemotherapy, and improve quality of life and satisfaction of patients after discharge.
我们探讨了智能手机医疗应用程序对接受放化疗的鼻咽癌患者并发症和生活质量的干预效果。
我们将首次接受放化疗的 132 例鼻咽癌患者按照随机数字表法分为对照组(67 例)和干预组(65 例)。对照组患者出院时给予标准护理,干预组患者出院后使用智能手机医疗应用程序。收集并分析两组患者的放化疗不良反应、并发症和生活质量数据。
两组患者出院时的放化疗并发症和生活质量无差异(P>0.05)。出院后 6 个月时,干预组口腔黏膜炎、口干、张口困难和鼻塞的发生率明显低于对照组,生活质量明显高于对照组(P<0.05)。
合理使用该智能手机应用程序可以提高出院后接受放化疗的鼻咽癌患者的锻炼依从性,减轻放化疗的不良反应和并发症,提高患者出院后的生活质量和满意度。