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2014 年科威特成年人口中前驱糖尿病和糖尿病的流行率。

The prevalence of pre-diabetes and diabetes in the Kuwaiti adult population in 2014.

机构信息

Dasman Diabetes Institute, Kuwait City, Kuwait.

Faculty of Medicine and Faculty of Public Health, Kuwait University, Kuwait.

出版信息

Diabetes Res Clin Pract. 2018 Oct;144:213-223. doi: 10.1016/j.diabres.2018.08.016. Epub 2018 Sep 1.

Abstract

BACKGROUND

Kuwait ranks among the top 20 countries worldwide in diabetes prevalence. This study's objectives were to assess the prevalence of pre-diabetes and diabetes in Kuwaiti adults.

METHODS

Kuwaiti citizens aged 18-69 years (n = 3915) were studied using the WHO's STEPwise survey methodology, including its Instrument for Chronic Disease Risk Factor Surveillance. Participants' demographics, medical history, physical measurements and blood biochemistry were assessed. A subset of 2561 individuals completed all three survey steps, including fasting plasma glucose (FPG) and HbA1c assays. The study assessed the prevalence of pre-diabetes (FPG 6.1-6.9 mmol/L or HbA1c level 5.7-6.4%) and diabetes (self-reported history of diabetes with prescription of diabetes medications or FPG ≥ 7 mmol/L or HbA1c level ≥6.5%).

RESULTS

The prevalence of pre-diabetes was 19.4% [95% CI: 17.9-21.0%] (By sex: Men, 19.3%; Women, 19.5%; p = 0.92; By age (years): 18-29 y, 13.9%; 30-44 y, 22.6%; 45-59 y, 25.8%; 60-69 y, 16.4%; p < 0.001). The prevalence of diabetes was 18.8% [17.3-20.4%] (By sex: Men, 20.4%; Women, 17.4%; p = 0.055; By age: 18-29 y, 6.6%; 30-44 y, 14.0%; 45-59 y, 36.7%; 60-69 y, 62.8%; p < 0.001), of whom 41.5% were previously undiagnosed. Diabetes prevalence was 27.4% among those with body mass index (BMI) ≥ 30 kg/m, 29% among those with elevated waist-hip ratio and 36% among those with hypertension. Diabetes was positively associated with BMI, waist-hip ratio and blood pressure level. Pre-diabetes was positively associated with BMI and waist-hip ratio, but not blood pressure level.

CONCLUSIONS

Almost 40% of Kuwaiti citizens had pre-diabetes or diabetes. Urgent public health action is needed to decrease diabetes prevalence and thus avoid associated morbidity and mortality.

摘要

背景

科威特的糖尿病患病率在全球排名前 20 位。本研究旨在评估科威特成年人的糖尿病前期和糖尿病患病率。

方法

采用世界卫生组织(WHO)的 STEPwise 调查方法对年龄在 18-69 岁的科威特公民(n=3915)进行研究,包括其慢性病风险因素监测工具。评估参与者的人口统计学、病史、身体测量和血液生化指标。有 2561 人完成了所有三个调查步骤,包括空腹血糖(FPG)和糖化血红蛋白(HbA1c)检测。该研究评估了糖尿病前期(FPG 6.1-6.9mmol/L 或 HbA1c 水平 5.7-6.4%)和糖尿病(自我报告的糖尿病病史,服用糖尿病药物或 FPG≥7mmol/L 或 HbA1c 水平≥6.5%)的患病率。

结果

糖尿病前期患病率为 19.4%[95%CI:17.9-21.0%](按性别:男性 19.3%;女性 19.5%;p=0.92;按年龄(岁):18-29 岁 13.9%;30-44 岁 22.6%;45-59 岁 25.8%;60-69 岁 16.4%;p<0.001)。糖尿病患病率为 18.8%[17.3-20.4%](按性别:男性 20.4%;女性 17.4%;p=0.055;按年龄:18-29 岁 6.6%;30-44 岁 14.0%;45-59 岁 36.7%;60-69 岁 62.8%;p<0.001),其中 41.5%为既往未确诊患者。BMI≥30kg/m2 的患者中糖尿病患病率为 27.4%,腰臀比升高的患者为 29%,高血压患者为 36%。糖尿病与 BMI、腰臀比和血压水平呈正相关。糖尿病前期与 BMI 和腰臀比呈正相关,但与血压水平无关。

结论

近 40%的科威特公民患有糖尿病前期或糖尿病。需要采取紧急的公共卫生行动来降低糖尿病的患病率,从而避免相关的发病率和死亡率。

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