Suzuki Hidetaka, Suzuki Shinya, Kamata Hayato, Sugama Yuka, Demachi Ken, Ikegawa Kiwako, Igarashi Takashi, Yamaguchi Masakazu
Department of Pharmacy, National Cancer Center Hospital East, National Research and Development Agency, Kashiwa, Japan.
J Oncol Pharm Pract. 2019 Oct;25(7):1558-1563. doi: 10.1177/1078155218798138. Epub 2018 Sep 4.
Collaboration between pharmacists, doctors, and nurses in outpatient treatment is beneficial; however, such services are limited in Japan due to the lack of a healthcare reimbursement fee for outpatient pharmacy services at outpatient clinic.
We evaluated the impact of a service in which clinical pharmacists collaborated with an oncologist at an outpatient clinic in the treatment of adverse drug reactions in outpatient cancer chemotherapy.
We performed a retrospective cohort study using patients' medical records and treatment diaries. Subjects were patients who received outpatient chemotherapy via a clinical pharmacist collaboration service provided by six outpatient pharmacists and an oncologist at an outpatient clinic between June and August 2016.
During the study period, the total number of outpatient services was 2508, with 2055 (81%) related to chemotherapy. The six outpatient pharmacists provided interventions to 498 of the 2055 cases (24%). Of the 498 interventions, 103 (20%), in addition to oncologist's prescription, were suggested treatments for adverse drug reactions due to cancer chemotherapy. Oncologists approved a total of 82 prescription suggestions from pharmacists (79%) to 63 patients. Fifty-seven percent ( = 47) of the adverse drug reactions were improved following the pharmacists' suggested prescriptions.
This is the first study to clarify the benefits of outpatient pharmacy services in which pharmacists collaborate with oncologists at an outpatient clinic for the management of adverse drug reactions in cancer patients in Japan.
药剂师、医生和护士在门诊治疗中的合作是有益的；然而，由于日本门诊诊所缺乏门诊药房服务的医疗报销费用，此类服务受到限制。
我们评估了一项服务的影响，即临床药剂师与门诊诊所的肿瘤学家合作治疗门诊癌症化疗中的药物不良反应。
我们使用患者的病历和治疗日记进行了一项回顾性队列研究。研究对象为2016年6月至8月期间通过6名门诊药剂师和一名门诊诊所肿瘤学家提供的临床药剂师合作服务接受门诊化疗的患者。
在研究期间，门诊服务总数为2508次，其中2055次（81%）与化疗有关。6名门诊药剂师对2055例病例中的498例（24%）进行了干预。在498次干预中，除肿瘤学家的处方外，有103次（20%）是针对癌症化疗药物不良反应的建议治疗。肿瘤学家总共批准了药剂师对63名患者提出的82条处方建议（79%）。按照药剂师建议的处方，57%（=47）的药物不良反应得到改善。
这是第一项阐明门诊药房服务益处的研究，在日本，门诊药房服务是药剂师与门诊诊所的肿瘤学家合作管理癌症患者药物不良反应。
