Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Structure. 2018 Sep 4;26(9):1166-1167. doi: 10.1016/j.str.2018.08.009.
RNAs are relatively difficult to crystallize because many sequence variants must be tested to obtain suitable crystal contacts. In this issue of Structure, Shoffner et al. (2018) report an in crystallo selection procedure that allows for the rapid generation of new RNA crystal contacts.
RNAs 相对较难结晶，因为必须测试许多序列变体以获得合适的晶体接触。在本期结构中，Shoffner 等人（2018）报告了一种在晶体中的选择程序，可快速生成新的 RNA 晶体接触。
