1Environmental Health Institute, National Environment Agency, 11 Biopolis Way, #04-03/04/05, Helios Block, Singapore, 138667 Singapore.
Veterinary Emergency and Specialty Hospital Pte Ltd, 2-14 Rochdale Road, Singapore, 535815 Singapore.
Antimicrob Resist Infect Control. 2018 Aug 31;7:106. doi: 10.1186/s13756-018-0399-9. eCollection 2018.
An analysis of 186 diagnostic reports collected from a veterinary clinic in Singapore between 2014 to 2016 showed that sick companion animals can carry bacteria that are of significance to human health. Among the 186 specimens submitted, 82 showed polymicrobial growth (45%, 82/186) and in total, 359 bacteria were isolated. Of the 359 bacteria reported, 45% (162/359) were multi-drug resistant and 18% (66/359) were extended-spectrum-beta-lactamase species. Resistance to broad-spectrum antibiotics were also observed among individual species. Namely, methicillin-resistance among (63%, 32/51) and (50%, 4/8); fluoroquinolone-resistance among (40%, 17/42) and carbapenem-resistance among (7%, 2/30) were noted. Our analysis suggests that sick pets may contribute to the pool of clinically relevant antibiotic-resistant bacteria and play a role in the spread of antibiotic resistance in Singapore. A more extensive study to better understand the extent of distribution and the factors affecting transmission of antibiotic-resistant bacteria to and from pets is necessary.
对 2014 年至 2016 年期间新加坡一家兽医诊所收集的 186 份诊断报告进行分析后表明，患病伴侣动物可能携带对人类健康具有重要意义的细菌。在提交的 186 个标本中，有 82 个显示出多种微生物生长（45%，82/186），总共分离出 359 种细菌。在所报告的 359 种细菌中，有 45%（162/359）为多药耐药菌，18%（66/359）为扩展谱β-内酰胺酶种。个别物种也观察到对广谱抗生素的耐药性。即，耐甲氧西林的 （63%，32/51）和 （50%，4/8）；耐氟喹诺酮的 （40%，17/42）和耐碳青霉烯的 （7%，2/30）。我们的分析表明，患病宠物可能有助于积累具有临床相关性的抗生素耐药菌，并在新加坡发挥抗生素耐药性传播的作用。有必要进行更广泛的研究，以更好地了解抗生素耐药菌在宠物中的分布程度和影响其向宠物传播的因素。
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