Nagata Shunichi, Ishihara Misa, Omasa Mitsugu, Nakanishi Takao, Motoyama Hideki
Department of Thoracic Surgery Kobe City Nishi-Kobe Medical Center Kobe Japan.
Department of Clinical Pathology Kobe City Nishi-Kobe Medical Center Kobe Japan.
Respirol Case Rep. 2018 Aug 31;6(7):e00361. doi: 10.1002/rcr2.361. eCollection 2018 Oct.
A 56-year-old female presented to our department with chest discomfort. Contrast-enhanced computed tomography (CT) revealed a cyst and nodule in the anterior mediastinum; positron emission tomography-CT showed an increased uptake in the nodule. Total thymectomy was performed to obtain a definitive diagnosis and treatment. A pathological diagnosis of multifocal thymic cysts with cholesterol granuloma was made. Microscopic examination revealed different-sized cysts scattered in the thymus. These cysts were filled with cholesterol clefts and manifested three different phase characters. The nodule comprised granuloma-containing cholesterol clefts. We report a rare case of a patient whose histopathology presented a series of cholesterol granuloma formations.
一名56岁女性因胸部不适前来我院就诊。增强计算机断层扫描（CT）显示前纵隔有一个囊肿和结节；正电子发射断层扫描-CT显示结节处摄取增加。行全胸腺切除术以明确诊断并进行治疗。病理诊断为多灶性胸腺囊肿伴胆固醇肉芽肿。显微镜检查发现胸腺内散在大小不一的囊肿。这些囊肿充满胆固醇裂隙，并呈现出三种不同的阶段特征。结节由含胆固醇裂隙的肉芽肿组成。我们报告了一例罕见病例，该患者的组织病理学表现为一系列胆固醇肉芽肿形成。
