Furuhira Chizu, Ohshima Akira, Shimada Kazuo, Kuroki Syoji, Nakano Kenji, Ishikawa Mikimasa, Yamamoto Hidetaka, Tanaka Masao
Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Breast Cancer. 2004;11(2):210-3. doi: 10.1007/BF02968304.
Cholesterol granuloma of the breast is a very rare benign disease with clinical and imaging features that are often indistinguishable from cancer preoperatively. We report a case of breast cholesterol granuloma accompanied by cancer. The patient was a 78-year-old woman who complained of a lump in her right breast. Mammography and ultrasonography showed a well-circumscribed mass. Fine needle aspiration cytology showed many cholesterol crystals and inflammatory cells without malignancy. With a diagnosis of cholesterol granuloma, tumor extirpation was performed. Histopathologic examination revealed cholesterol granuloma together with breast cancer, and additional partial mastectomy was subsequently performed. It is noted that breast cholesterol granuloma could be accompanied by cancer.
乳腺胆固醇肉芽肿是一种非常罕见的良性疾病，其临床和影像学特征在术前常与癌症难以区分。我们报告一例伴有癌症的乳腺胆固醇肉芽肿病例。患者为一名78岁女性，主诉右乳有肿块。乳房X线摄影和超声检查显示有一个边界清晰的肿块。细针穿刺细胞学检查显示有许多胆固醇结晶和炎性细胞，无恶性迹象。诊断为胆固醇肉芽肿后，进行了肿瘤切除。组织病理学检查显示胆固醇肉芽肿合并乳腺癌，随后进行了额外的局部乳房切除术。值得注意的是，乳腺胆固醇肉芽肿可能伴有癌症。
