[干细胞微环境与再生医学]

[STEM CELL NICHES AND REGENERATIVE MEDICINE].

作者信息

Vasiliev A V, Vorotelyak E A, Terskikh V V

出版信息

Ross Fiziol Zh Im I M Sechenova. 2016 Mar;102(3):241-61.

Abstract

The review is devoted to modern state of science in the area of stem cell niches. Fundamental characteristics of niche including extracellular matrix are considered. Key principles of niche functioning are demonstrated by the example of hematopoietic and epithelial cells. Special section discusses the use of stem cells and their microenvironment in regenerative medicine.

摘要

这篇综述致力于干细胞生态位领域的现代科学现状。文中考虑了包括细胞外基质在内的生态位的基本特征。通过造血细胞和上皮细胞的例子展示了生态位发挥功能的关键原则。特别章节讨论了干细胞及其微环境在再生医学中的应用。