Hoda Raza S, Pitman Martha B
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA.
Surg Pathol Clin. 2018 Sep;11(3):563-588. doi: 10.1016/j.path.2018.04.005.
The diagnostic approach to pancreaticobiliary disease requires a multidisciplinary team in which the cytopathologist plays a crucial role. Fine-needle aspiration, obtained by endoscopic ultrasound, is the diagnostic test of choice for pancreatic lesions. Preoperative clinical management depends on many factors, many of which rely on accurate cytologic assessment. Pancreaticobiliary cytology is wrought with diagnostic pitfalls. Clinical history, imaging studies, cytology samples, and ancillary tests, including immunohistochemistry, biochemical analysis, and genetic sequencing, are integral to forming a complete diagnosis and guiding optimal patient management. This article reviews clinical aspects and the diagnostic work-up of commonly encountered diagnostic entities within the field of pancreatic cytology.
胰腺胆管疾病的诊断方法需要多学科团队参与，其中细胞病理学家发挥着关键作用。通过内镜超声获取的细针穿刺活检是胰腺病变的首选诊断检测方法。术前临床管理取决于多种因素，其中许多因素依赖于准确的细胞学评估。胰腺胆管细胞学诊断存在诸多陷阱。临床病史、影像学检查、细胞学样本以及辅助检测，包括免疫组织化学、生化分析和基因测序，对于形成完整诊断及指导最佳患者管理至关重要。本文回顾了胰腺细胞学领域常见诊断实体的临床方面及诊断检查。
