Department of Pathology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: https://twitter.com/melaniekwan.
Department of Pathology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Surg Pathol Clin. 2024 Sep;17(3):441-452. doi: 10.1016/j.path.2024.04.007. Epub 2024 Jun 15.
Pancreatic lesions can be solid or cystic and comprise a wide range of benign, premalignant, and malignant entities. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is the current primary sampling method for the preoperative diagnosis of pancreatic lesions. Optimal handling of cytology/small tissue specimens is critical to ensure that the often-scant diagnostic material is appropriately utilized for ancillary and/or molecular studies when appropriate. Ultimately, evaluation of EUS-FNA cytology and small biopsy material can provide accurate and timely diagnoses to guide patient management and triage them to surveillance or surgical intervention.
胰腺病变可以是实性或囊性的,包括广泛的良性、癌前病变和恶性病变。内镜超声引导下细针抽吸(EUS-FNA)是目前术前诊断胰腺病变的主要采样方法。细胞学/小组织标本的最佳处理对于确保在适当的情况下,将通常有限的诊断材料充分用于辅助和/或分子研究至关重要。最终,EUS-FNA 细胞学和小活检材料的评估可以提供准确和及时的诊断,以指导患者管理并将其分诊至监测或手术干预。