Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?
作者信息
Haass Nikolas K
出版信息
Melanoma Manag. 2015 May;2(2):93-95. doi: 10.2217/mmt.15.1. Epub 2015 May 18.
Abstract
摘要
相似文献
1
Dynamic tumor heterogeneity in melanoma therapy: how do we address this in a novel model system?黑色素瘤治疗中的动态肿瘤异质性：我们如何在一个新的模型系统中解决这个问题？
Melanoma Manag. 2015 May;2(2):93-95. doi: 10.2217/mmt.15.1. Epub 2015 May 18.
2
Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma.黑色素瘤三维细胞培养模型中的实时细胞周期成像
Methods Mol Biol. 2017;1612:401-416. doi: 10.1007/978-1-4939-7021-6_29.
3
Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma, Quantitative Analysis, Optical Clearing, and Mathematical Modeling.实时细胞周期成像在黑色素瘤 3D 细胞培养模型中的应用：定量分析、光学透明化和数学建模。
Methods Mol Biol. 2024;2764:291-310. doi: 10.1007/978-1-0716-3674-9_19.
4
Real-time cell cycle imaging during melanoma growth, invasion, and drug response.黑色素瘤生长、侵袭及药物反应过程中的实时细胞周期成像
Pigment Cell Melanoma Res. 2014 Sep;27(5):764-76. doi: 10.1111/pcmr.12274. Epub 2014 Jun 27.
5
Cell cycle-tailored targeting of metastatic melanoma: Challenges and opportunities.靶向转移性黑色素瘤的细胞周期调控：挑战与机遇。
Exp Dermatol. 2017 Jul;26(7):649-655. doi: 10.1111/exd.13303. Epub 2017 Apr 20.
6
Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids.基于成像和流式细胞术的三维黑色素瘤球体中细胞位置和细胞周期分析
J Vis Exp. 2015 Dec 28(106):e53486. doi: 10.3791/53486.
7
Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance.微环境驱动的动态异质性和表型可塑性作为黑色素瘤治疗耐药的一种机制
Front Oncol. 2018 May 24;8:173. doi: 10.3389/fonc.2018.00173. eCollection 2018.
8
Future perspectives in melanoma research : Meeting report from the "Melanoma Bridge". Napoli, December 1st-4th 2015.黑色素瘤研究的未来展望：“黑色素瘤桥梁”会议报告。那不勒斯，2015年12月1日至4日
J Transl Med. 2016 Nov 15;14(1):313. doi: 10.1186/s12967-016-1070-y.
9
Phenotypic tumour cell plasticity as a resistance mechanism and therapeutic target in melanoma.表型肿瘤细胞可塑性作为黑色素瘤的一种耐药机制和治疗靶点
Eur J Cancer. 2016 May;59:109-112. doi: 10.1016/j.ejca.2016.02.023. Epub 2016 Mar 26.
10
Knockdown of FBXO22 inhibits melanoma cell migration, invasion and angiogenesis via the HIF-1α/VEGF pathway.敲低 FBXO22 通过 HIF-1α/VEGF 通路抑制黑色素瘤细胞迁移、侵袭和血管生成。
Invest New Drugs. 2020 Feb;38(1):20-28. doi: 10.1007/s10637-019-00761-z. Epub 2019 Mar 18.
引用本文的文献
1
Real-Time Cell Cycle Imaging in a 3D Cell Culture Model of Melanoma, Quantitative Analysis, Optical Clearing, and Mathematical Modeling.实时细胞周期成像在黑色素瘤 3D 细胞培养模型中的应用：定量分析、光学透明化和数学建模。
Methods Mol Biol. 2024;2764:291-310. doi: 10.1007/978-1-0716-3674-9_19.
2
Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy.黑色素瘤干细胞通过外泌体 miR-1268a 抑制自噬促进转移。
Biol Res. 2022 Oct 1;55(1):29. doi: 10.1186/s40659-022-00397-z.
3
Low-metastatic melanoma cells acquire enhanced metastatic capability via exosomal transfer of miR-199a-1-5p from highly metastatic melanoma cells.低转移性黑色素瘤细胞通过从高转移性黑色素瘤细胞外泌体转移miR-199a-1-5p获得增强的转移能力。
Cell Death Discov. 2022 Apr 9;8(1):188. doi: 10.1038/s41420-022-00993-8.
4
Association of homogeneous inflamed gene signature with a better outcome in patients with metastatic melanoma treated with MAGE-A3 immunotherapeutic.在接受MAGE - A3免疫治疗的转移性黑色素瘤患者中，同质炎症基因特征与更好的预后相关。
ESMO Open. 2018 Jul 25;3(5):e000384. doi: 10.1136/esmoopen-2018-000384. eCollection 2018.
5
Microenvironment-Driven Dynamic Heterogeneity and Phenotypic Plasticity as a Mechanism of Melanoma Therapy Resistance.微环境驱动的动态异质性和表型可塑性作为黑色素瘤治疗耐药的一种机制
Front Oncol. 2018 May 24;8:173. doi: 10.3389/fonc.2018.00173. eCollection 2018.
6
Therapeutic implications of melanoma heterogeneity.黑色素瘤异质性的治疗意义。
Exp Dermatol. 2016 Jul;25(7):497-500. doi: 10.1111/exd.13002. Epub 2016 May 19.
7
Imaging- and Flow Cytometry-based Analysis of Cell Position and the Cell Cycle in 3D Melanoma Spheroids.基于成像和流式细胞术的三维黑色素瘤球体中细胞位置和细胞周期分析
J Vis Exp. 2015 Dec 28(106):e53486. doi: 10.3791/53486.
本文引用的文献
1
Modeling Melanoma In Vitro and In Vivo.体外和体内黑色素瘤建模。
Healthcare (Basel). 2013 Dec 23;2(1):27-46. doi: 10.3390/healthcare2010027.
2
A stress-induced early innate response causes multidrug tolerance in melanoma.应激诱导的早期先天反应导致黑色素瘤的多药耐受性。
Oncogene. 2015 Aug 20;34(34):4448-59. doi: 10.1038/onc.2014.372. Epub 2014 Nov 24.
3
Real-time cell cycle imaging during melanoma growth, invasion, and drug response.黑色素瘤生长、侵袭及药物反应过程中的实时细胞周期成像
Pigment Cell Melanoma Res. 2014 Sep;27(5):764-76. doi: 10.1111/pcmr.12274. Epub 2014 Jun 27.
4
Melanoma never says die.黑色素瘤永不言败。
Exp Dermatol. 2014 Jul;23(7):471-2. doi: 10.1111/exd.12400.
5
Melanoma's connections to the tumour microenvironment.黑色素瘤与肿瘤微环境的联系。
Pathology. 2013 Aug;45(5):443-52. doi: 10.1097/PAT.0b013e328363b3bd.
6
DNA repair and cell cycle checkpoint defects as drivers and therapeutic targets in melanoma.DNA 修复和细胞周期检查点缺陷作为黑色素瘤的驱动因素和治疗靶点。
Pigment Cell Melanoma Res. 2013 Nov;26(6):805-16. doi: 10.1111/pcmr.12136. Epub 2013 Aug 5.
7
In vitro three-dimensional tumor microenvironment models for anticancer drug discovery.用于抗癌药物发现的体外三维肿瘤微环境模型。
Expert Opin Drug Discov. 2008 Jan;3(1):1-10. doi: 10.1517/17460441.3.1.1.
8
Melanoma: from mutations to medicine.黑素瘤：从突变到医学。
Genes Dev. 2012 Jun 1;26(11):1131-55. doi: 10.1101/gad.191999.112.
9
Hallmarks of cancer: the next generation.癌症的特征：下一代。
Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013.
10
Moving targets that drive cancer progression.推动癌症进展的移动靶标。
N Engl J Med. 2010 Aug 26;363(9):885-6. doi: 10.1056/NEJMcibr1006328.
Zotero 插件