Markle-Reid Maureen, Ploeg Jenny, Valaitis Ruta, Duggleby Wendy, Fisher Kathryn, Fraser Kimberly, Ganann Rebecca, Griffith Lauren E, Gruneir Andrea, McAiney Carrie, Williams Allison
School of Nursing, McMaster University, Hamilton, Ontario, Canada.
Health Research Methods, Evidence and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
J Comorb. 2018 Jul 31;8(1):2235042X18789508. doi: 10.1177/2235042X18789508. eCollection 2018.
The goal of the Aging, Community and Health Research Unit (ACHRU) is to promote optimal aging at home for older adults with multimorbidity (≥2 chronic conditions) and to support their family/friend caregivers. This protocol paper reports the rationale and plan for this patient-oriented, cross-jurisdictional research program.
The objectives of the ACHRU research program are (i) to codesign integrated and person-centered interventions with older adults, family/friend caregivers, and providers; (ii) to examine the feasibility of newly designed interventions; (iii) to determine the intervention effectiveness on Triple Aim outcomes: health, patient/caregiver experience, and cost; (iv) to examine intervention context and implementation barriers and facilitators; (v) to use diverse integrated knowledge translation (IKT) strategies to engage knowledge users to support scalability and sustainability of effective interventions; and (vi) to build patient-oriented research capacity.
The research program was informed by the Knowledge-to-Action Framework and the Complexity Model. Six individual studies were conceptualized as integrated pieces of work. The results of the three initial descriptive studies will inform and be followed by three pragmatic randomized controlled trials. IKT and capacity building activities will be embedded in all six studies and tailored to the unique focus of each study.
This research program will inform the development of effective and scalable person-centered interventions that are sustainable through interagency and intersectoral partnerships with community-based agencies, policy makers, and other health and social service agencies. Implementation of these interventions has the potential to transform health-care services and systems and improve the quality of life for older adults with multimorbidity and their caregivers.
NCT02428387 (study 4), NCT02158741 (study 5), and NCT02209285 (study 6).
老龄化、社区与健康研究单位（ACHRU）的目标是促进患有多种疾病（≥2种慢性病）的老年人在家中实现最佳老龄化，并为其家庭/朋友护理者提供支持。本方案文件报告了这个以患者为导向的跨辖区研究项目的基本原理和计划。
ACHRU研究项目的目标是：（i）与老年人、家庭/朋友护理者及提供者共同设计综合且以人为本的干预措施；（ii）检验新设计干预措施的可行性；（iii）确定干预措施对三重目标结果（健康、患者/护理者体验和成本）的有效性；（iv）研究干预背景以及实施障碍和促进因素；（v）运用多种综合知识转化（IKT）策略，让知识使用者参与进来，以支持有效干预措施的可扩展性和可持续性；（vi）建立以患者为导向的研究能力。
该研究项目以知识到行动框架和复杂性模型为依据。六项独立研究被概念化为综合的工作内容。三项初始描述性研究的结果将为三项实用随机对照试验提供信息并随后进行。IKT和能力建设活动将融入所有六项研究，并根据每项研究的独特重点进行调整。
本研究项目将为有效且可扩展的以人为本干预措施的开发提供信息，这些干预措施可通过与社区机构、政策制定者以及其他健康和社会服务机构建立跨机构和跨部门伙伴关系来实现可持续性。实施这些干预措施有可能改变医疗服务和系统，并改善患有多种疾病的老年人及其护理者的生活质量。
NCT02428387（研究4）、NCT02158741（研究5）和NCT02209285（研究6）。
