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回肠原发性经典型霍奇金淋巴瘤与结肠 Epstein-Barr 病毒黏膜溃疡性疾病：两种实体的比较。

Primary classic Hodgkin lymphoma of the ileum and Epstein-Barr virus mucocutaneous ulcer of the colon: two entities compared.

机构信息

Pathology Unit, Azienda Unità Sanitaria Locale/IRCCS, Reggio Emilia, Italy.

Department of Oncology and Advanced Technologies, Surgical Oncology Unit, Azienda Unità Sanitaria Locale/IRCCS, Reggio Emilia, Italy.

出版信息

Virchows Arch. 2019 Jan;474(1):117-123. doi: 10.1007/s00428-018-2451-9. Epub 2018 Sep 7.

DOI:10.1007/s00428-018-2451-9
PMID:30194489
Abstract

Primary classic Hodgkin lymphoma of the gastrointestinal tract represents a rare occurrence. A full patient's work-up is essential in order to exclude a secondary intestinal involvement. Histologically Epstein-Barr virus mucocutaneous ulcer closely resembles Hodgkin lymphoma. The differential diagnosis between these two entities is relevant, since both the therapeutic approach and the clinical behavior are different. Herein, we describe a case of primary classic Hodgkin lymphoma arising in the ileum and a case of Epstein-Barr virus mucocutaneous ulcer of the colon, focusing on the main clinicopathological differences.

摘要

原发性胃肠道经典型霍奇金淋巴瘤较为罕见。为了排除继发性肠道受累，全面的患者检查至关重要。组织学上，EB 病毒黏膜溃疡与霍奇金淋巴瘤非常相似。这两种实体之间的鉴别诊断很重要，因为它们的治疗方法和临床行为不同。在此，我们描述了一例发生在回肠的原发性经典型霍奇金淋巴瘤和一例发生在结肠的 EBV 黏膜溃疡病例，重点介绍了主要的临床病理差异。

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本文引用的文献

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Leuk Res. 2018 Aug;71:1-5. doi: 10.1016/j.leukres.2018.06.008. Epub 2018 Jun 17.
2
Primary classical Hodgkin lymphoma of rectum: Report of an extremely rare case and review of the literature.直肠原发性经典型霍奇金淋巴瘤：1例极其罕见病例报告并文献复习
Indian J Pathol Microbiol. 2017 Jul-Sep;60(3):412-414. doi: 10.4103/IJPM.IJPM_767_16.
3
A rare case of Epstein-Barr virus mucocutaneous ulcer of the colon.
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Life (Basel). 2021 Oct 11;11(10):1069. doi: 10.3390/life11101069.
4
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Cancers (Basel). 2021 Sep 12;13(18):4578. doi: 10.3390/cancers13184578.
5
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Cancers (Basel). 2021 Sep 8;13(18):4527. doi: 10.3390/cancers13184527.
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