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基于香豆素的高灵敏荧光化学传感器用于选择性检测锌离子。

A coumarin based highly sensitive fluorescent chemosensor for selective detection of zinc ion.

机构信息

Department of Chemistry, University of Isfahan, 81746-73441 Isfahan, Iran.

Department of Chemistry, University of Isfahan, 81746-73441 Isfahan, Iran.

出版信息

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jan 15;207:16-22. doi: 10.1016/j.saa.2018.08.061. Epub 2018 Aug 30.

DOI:10.1016/j.saa.2018.08.061
PMID:30195181
Abstract

A very effective and highly sensitive fluorescent chemosensor, based on 4-hydroxycoumarin skeleton substituted by benzothiazole moiety was synthesized and investigated for the detection of zinc ion. This chemosensor displays highly selective and sensitive fluorescence enhancement to Zn over other metal ions examined in solution and in biological systems. The detection limit for the fluorescent chemosensor 1 toward Zn was 3.58 × 10 M. A simple and efficient approach was improved for the synthesis of chemosensor 1 starting from 4-hydroxycoumarin.

摘要

一种基于苯并噻唑取代的 4-羟基香豆素骨架的非常有效且高灵敏度的荧光化学传感器被合成,并研究了其对锌离子的检测。该化学传感器在溶液中和生物体系中对 Zn 的选择性和灵敏度荧光增强显示出高度选择性和灵敏度。荧光化学传感器 1 对 Zn 的检测限为 3.58×10-7M。从 4-羟基香豆素出发,改进了一种简单高效的合成化学传感器 1 的方法。

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