Drobiazgo L D, Prokopenko L G
Kardiologiia. 1977 Mar;17(3):118-24.
The effect of serum of rabbits receiving an atherogenic diet on the biosynthesis of antibodies in intact animals was studied. The serum of rabbit kept on atherogenic diets for 6 weeks produced no effect upon the antibody formation when injected to intact rabbits simultanously with antigens. The serum of rabbits receiving cholesterol with their meals for 13 weeks stimulated antibody formation when injected simultaneously with antigens to intact animals. Incubation of the serum of rabbits kept on an atherogenic diet for 13 weeks with the polyvalent proteinase inhibitor Trasylol completely deprived it of its immunostimulating properties.
研究了接受致动脉粥样化饮食的兔子血清对正常动物抗体生物合成的影响。给兔子喂食致动脉粥样化饮食6周后，其血清在与抗原同时注射给正常兔子时，对抗体形成没有影响。给兔子连续13周在食物中添加胆固醇，其血清在与抗原同时注射给正常动物时，会刺激抗体形成。将喂食致动脉粥样化饮食13周的兔子血清与多价蛋白酶抑制剂抑肽酶一起孵育后，其免疫刺激特性完全丧失。
