Zakirov U B, Shaislamov B Sh, Teshabaev D Ia
Farmakol Toksikol. 1986 Jul-Aug;49(4):28-31.
Effect of a central cholinolytic drug amizyl on the activity of some digestive enzymes involved in carbohydrate hydrolysis was studied in experiments on control rats and animals exposed to immobilization stress. The experiments showed that amizyl administration modifies the activity of carbohydrases that could affect disintegration and assimilation of carbohydrases. Preliminary administration of the drug was shown to prevent substantially the changes in the enzyme activity occurring during stress situation.
在对照大鼠和遭受固定应激的动物实验中,研究了中枢性抗胆碱能药物阿米齐尔对参与碳水化合物水解的某些消化酶活性的影响。实验表明,给予阿米齐尔会改变碳水化合物酶的活性,这可能会影响碳水化合物的分解和吸收。结果显示,预先给药该药物可显著预防应激状态下发生的酶活性变化。