Zakirov U B, Teshabaev D Ia
Farmakol Toksikol. 1988 May-Jun;51(3):54-6.
In experiments on albino rats it was shown that a single (50, 100, 200 and 300 mg/kg) and prolonged (200 mg/kg) administration of metacine produced changes in the activity of carbohydrases (alpha-, gamma-amylases and saccharase) of the intestine. A preliminary treatment with the drug weakened changes in their activity observed during stress situations.
在对白化大鼠的实验中发现,单次给予美他辛(50、100、200和300毫克/千克)以及长期给予(200毫克/千克)会导致肠道中碳水化合物酶(α-淀粉酶、γ-淀粉酶和蔗糖酶)的活性发生变化。药物预处理减轻了应激状态下观察到的这些酶活性的变化。