Wu Ting-Kui, Meng Yang, Liu Hao, Hong Ying, Wang Bei-Yu, Rong Xin, Ding Chen, Chen Hua
Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Medicine (Baltimore). 2018 Sep;97(36):e11755. doi: 10.1097/MD.0000000000011755.
The outcomes of cervical disc arthroplasty (CDA) following a previous fusion are ill -defined. The aim of this study was to share our experience and to assess mid-term outcomes in patients receiving CDA adjacent to a previous fusion compared with primary CDA.Patients with cervical radiculopathy and/or myelopathy or patients who had undergone a previous cervical fusion surgery and had developed adjacent segment disease (ASD) between January 2008 and April 2013 were enrolled. Clinical and radiographic outcomes were compared for patients undergoing CDA at a level adjacent to a previous fusion (previous group) and those undergoing primary CDA (primary group).Fifty-two patients in the primary group and 9 patients in the previous group had adequate follow-up data. The mean follow-up periods were 61.96 months and 61.78 months, respectively. The clinical outcomes all significantly improved after surgery, and no significant difference was found between groups. The disc height and range of motion of the operated level were preserved, and the values were similar between groups. Subsidence occurred in 2 (3.8%) patients in the primary group and 1 (11.11%) patient in the previous group. Heterotopic ossification (HO) was detected in 4 (44.44%) patients in the previous group and 18 (34.62%) patients in the primary group. None of the patients required reoperation.Patients treated with a Prestige-LP disc maintained improved clinical outcomes and segmental motion in both the primary and previous groups. Additionally, CDA-treated patients who had a previous fusion surgery could safely undergo the surgery with complication rates similar to that of the first CDA surgery after 48 months of follow-up. CDA adjacent to a previous fusion may be an alternative treatment strategy in the future.
先前融合术后颈椎间盘置换术(CDA)的结果尚不明确。本研究的目的是分享我们的经验,并评估与初次CDA相比,在先前融合部位附近接受CDA的患者的中期结果。纳入2008年1月至2013年4月期间患有颈椎神经根病和/或脊髓病的患者,或先前接受过颈椎融合手术并出现相邻节段疾病(ASD)的患者。比较在先前融合部位附近节段接受CDA的患者(先前组)和接受初次CDA的患者(初次组)的临床和影像学结果。初次组52例患者和先前组9例患者有足够的随访数据。平均随访时间分别为61.96个月和61.78个月。术后临床结果均显著改善,两组间无显著差异。手术节段的椎间盘高度和活动范围得以保留,两组间数值相似。初次组2例(3.8%)患者和先前组1例(11.11%)患者出现下沉。先前组4例(44.44%)患者和初次组18例(34.62%)患者检测到异位骨化(HO)。所有患者均无需再次手术。在初次组和先前组中,使用Prestige-LP椎间盘治疗的患者临床结果均得到改善,节段活动得以维持。此外,接受过先前融合手术且接受CDA治疗的患者在随访48个月后可安全接受手术,并发症发生率与首次CDA手术相似。在先前融合部位附近进行CDA可能是未来一种替代治疗策略。