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Enhancement of ECT benefit by yohimbine.

作者信息

Sachs G S, Pollack M H, Brotman A W, Farhadi A M, Gelenberg A J

出版信息

J Clin Psychiatry. 1986 Oct;47(10):508-10.

PMID:3020009
Abstract

Three patients with major depression who were pretreated with yohimbine 10 mg p.o. showed a dramatic response without major adverse effects following two electroconvulsive treatments (ECT). The hypothesis that the alpha 2-adrenergic antagonist yohimbine accelerates ECT-induced postsynaptic beta-adrenergic receptor down-regulation is discussed.

摘要

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