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尼日利亚大学生对暴露前和暴露后预防措施的知晓与使用情况:一项横断面调查的结果

Awareness and use of pre-exposure and postexposure prophylaxes among Nigerian university students: Findings from a cross-sectional survey.

作者信息

Ajayi Anthony Idowu, Ismail Kafayat Olanike, Adeniyi Oladele Vincent, Akpan Wilson

机构信息

Department of Sociology, Faculty of Social Sciences and Humanities, University of Fort Hare, East London, South Africa Department of Sociology, University of Ilorin, Ilorin, Nigeria Department of Microbiology, Faculty of Sciences and Agriculture, University of Fort Hare, Alice, South Africa.

出版信息

Medicine (Baltimore). 2018 Sep;97(36):e12226. doi: 10.1097/MD.0000000000012226.

Abstract

Despite the recent advances in biomedical preventive strategies, young adults-especially adolescent girls- continue to be disproportionately at risk of acquiring HIV. To avert this trend, it is critical that access to HIV preventive strategies, such as pre-exposure prophylaxis (PrEP) and postexposure prophylaxis be expanded, especially in sub-Saharan Africa, where young adults are known to engage in risky sexual practices. This study examined awareness levels and use of pre-exposure prophylaxis (PrEP) and postexposure prophylaxis (PEP) among Nigerian university students.A cross-sectional survey was conducted among 800 students selected using stratified random sampling at 2 Nigerian universities. Descriptive and inferential statistics were used for data analysis on 784 complete responses.The levels of awareness of PrEP and PEP were 18.9% and 25.4%, respectively. Ever tested for human immunodeficiency virus [HIV] (AOR: 1.58; 95% CI: 1.04-2.42) and knowledge of partner's HIV status (AOR: 1.87; 95% CI: 1.25-2.79) were the significant determinants of awareness to PrEP. In contrast, only ever tested for HIV (AOR: 1.50; 95% CI: 1.02-2.19), knowledge of partner's HIV status (AOR: 1.55; 95% CI: 1.07-2.24), ever used condoms (AOR: 1.65; 95% CI: 1.04-2.62), and nude exchanges (AOR: 1.62; 95% CI: 1.13-2.31) were independent determinants of awareness of PEP. Only a few students had seen (5.6%) or used (1.5%) any prophylaxes.The study findings indicate a low level of awareness and use of PrEP and PEP. To ensure no one is left behind in the goal of elimination of new HIV infections, intervention to expand access to these preventive strategies is needed in the study settings.

摘要

尽管生物医学预防策略最近取得了进展,但年轻人,尤其是青春期女孩,感染艾滋病毒的风险仍然过高。为避免这一趋势,扩大获得艾滋病毒预防策略的机会至关重要,如暴露前预防(PrEP)和暴露后预防,特别是在撒哈拉以南非洲,那里的年轻人有危险性行为。本研究调查了尼日利亚大学生对暴露前预防(PrEP)和暴露后预防(PEP)的知晓水平和使用情况。在尼日利亚两所大学采用分层随机抽样选取800名学生进行了横断面调查。对784份完整回复进行数据分析时使用了描述性和推断性统计。PrEP和PEP的知晓水平分别为18.9%和25.4%。接受过人类免疫缺陷病毒(HIV)检测(调整后比值比[AOR]:1.58;95%置信区间[CI]:1.04 - 2.42)以及了解性伴侣的HIV状况(AOR:1.87;95% CI:1.25 - 2.79)是PrEP知晓率的重要决定因素。相比之下,只有接受过HIV检测(AOR:1.50;95% CI:1.02 - 2.19)、了解性伴侣的HIV状况(AOR:1.55;95% CI:1.07 - 2.24)、使用过避孕套(AOR:1.65;95% CI:1.04 - 2.62)以及有过裸聊行为(AOR:1.62;95% CI:1.13 - 2.31)是PEP知晓率的独立决定因素。只有少数学生见过(5.6%)或使用过(1.5%)任何预防措施。研究结果表明PrEP和PEP的知晓率和使用率较低。为确保在消除新的HIV感染目标中不落下任何人,在研究环境中需要采取干预措施以扩大获得这些预防策略的机会。

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