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确定暴露前预防信息披露的障碍及应对策略:参与性交易的乌干达少女的经历——一项定性研究

Identifying barriers and coping strategies for pre-exposure prophylaxis disclosure: experiences of Ugandan adolescent girls engaged in transactional sex-a qualitative study.

作者信息

Mwima Simon, Bogart Laura M, Neema Steela, Komo Richard, Obbo Stephen

机构信息

Department of Social Work, University of Illinois Urbana Champagne, Champaign, IL, United States.

Bukedi Prevention Institute, Mbale, Uganda.

出版信息

Front Glob Womens Health. 2025 Mar 20;6:1517448. doi: 10.3389/fgwh.2025.1517448. eCollection 2025.

DOI:10.3389/fgwh.2025.1517448
PMID:40182227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11965671/
Abstract

INTRODUCTION

The disclosure of oral pre-exposure prophylaxis (PrEP) use among adolescent girls engaged in transactional sex in Uganda is a complex process shaped by stigma, fear of judgment, misconceptions, and the threat of violence. This qualitative study explores the strategies these adolescents use to navigate these challenges, drawing on resilience theory and asset-based approaches.

METHODS

Between April 2018 and May 2019, cross-sectional semi-structured interviews were conducted with Ugandan adolescent girls aged 18-24 engaged in transactional sex to explore their experiences of PrEP disclosure. Data were analyzed using a thematic network analysis approach, focusing on how participants managed the social and psychological barriers to disclosure.

RESULTS

The study found that stigma, misconceptions about PrEP, and fear of judgment or violence from clients and families were significant barriers to disclosure. However, adolescent girls employed multiple strategies to navigate these challenges. These included relying on peer support, selective disclosure to trusted individuals, and drawing on personal strength and resilience. Support from healthcare providers and access to youth-friendly health services further helped participants manage the risks associated with PrEP disclosure. Many participants used a combination of these strategies, adapting their approach to different social contexts.

CONCLUSION

This study highlights the complex strategies adolescent girls engaged in transactional sex in Uganda use to disclose PrEP use amidst significant barriers. The findings emphasize the need for targeted interventions that focus on strengthening peer support, enhancing the role of healthcare providers, and creating safe spaces for disclosure. By integrating these strategies into PrEP delivery models, public health efforts can empower these vulnerable populations to disclose and adhere to PrEP more confidently, improving HIV prevention outcomes.

摘要

引言

在乌干达,从事性交易的少女中披露口服暴露前预防(PrEP)的使用情况是一个复杂的过程,受到耻辱感、对评判的恐惧、误解以及暴力威胁的影响。这项定性研究借鉴复原力理论和基于资产的方法,探讨这些青少年用于应对这些挑战的策略。

方法

在2018年4月至2019年5月期间,对年龄在18 - 24岁、从事性交易的乌干达少女进行了横断面半结构化访谈,以探讨她们披露PrEP使用情况的经历。使用主题网络分析方法对数据进行分析,重点关注参与者如何应对披露的社会和心理障碍。

结果

研究发现,耻辱感、对PrEP的误解以及对来自客户和家庭的评判或暴力的恐惧是披露的重大障碍。然而,少女们采用了多种策略来应对这些挑战。这些策略包括依靠同伴支持、有选择地向信任的人披露,以及利用个人力量和复原力。医疗保健提供者的支持和获得对青少年友好的健康服务进一步帮助参与者管理与PrEP披露相关的风险。许多参与者结合使用这些策略,根据不同的社会背景调整方法。

结论

本研究强调了乌干达从事性交易的少女在存在重大障碍的情况下披露PrEP使用情况所采用的复杂策略。研究结果强调了有针对性干预措施的必要性,这些措施应侧重于加强同伴支持、增强医疗保健提供者的作用以及为披露创造安全空间。通过将这些策略纳入PrEP提供模式,公共卫生工作可以使这些弱势群体更自信地披露和坚持PrEP,改善艾滋病毒预防成果。

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本文引用的文献

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Applying implementation science frameworks to understand why fisherfolk continue or discontinue pre-exposure prophylaxis for HIV prevention in Uganda: a qualitative analysis.运用实施科学框架理解乌干达渔民继续或停止艾滋病毒暴露前预防措施的原因:一项定性分析
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Enhanced Oral Pre-exposure Prophylaxis (PrEP) Implementation for Ugandan Fisherfolk: Pilot Intervention Outcomes.增强乌干达渔民的口服暴露前预防(PrEP)实施:试点干预结果。
AIDS Behav. 2024 Oct;28(10):3512-3524. doi: 10.1007/s10461-024-04432-w. Epub 2024 Jul 19.
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HIV pre-exposure prophylaxis uptake, retention and adherence among female sex workers in sub-Saharan Africa: a systematic review.撒哈拉以南非洲地区女性性工作者中 HIV 暴露前预防的使用、保留和坚持情况:系统评价。
BMJ Open. 2024 Apr 25;14(4):e076545. doi: 10.1136/bmjopen-2023-076545.
4
"Take services to the people": strategies to optimize uptake of PrEP and harm reduction services among people who inject drugs in Uganda.“将服务送到人民手中”:乌干达优化注射吸毒人群接受 PrEP 和减少伤害服务的策略。
Addict Sci Clin Pract. 2024 Feb 23;19(1):13. doi: 10.1186/s13722-024-00444-y.
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Effectiveness of PrEPTECH: Findings From a 180-Day Randomized Controlled Trial of a Pre-Exposure Prophylaxis Telehealth Intervention.PrEPTECH 的有效性:一项为期 180 天的暴露前预防远程医疗干预随机对照试验的结果。
J Acquir Immune Defic Syndr. 2024 Apr 15;95(5):463-469. doi: 10.1097/QAI.0000000000003375. Epub 2024 Mar 11.
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Family influences on oral PrEP use among adolescent girls and young women in Kenya and South Africa.家庭对肯尼亚和南非青春期女孩和年轻妇女口服暴露前预防(PrEP)使用的影响。
PLoS One. 2023 Nov 14;18(11):e0292529. doi: 10.1371/journal.pone.0292529. eCollection 2023.
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The Effect of Disclosure of PrEP Use on Adherence Among African Young Women in an Open-Label PrEP Study: Findings from HPTN 082.在一项开放标签的 PrEP 研究中,公开披露 PrEP 使用对非洲年轻女性的依从性的影响:来自 HPTN 082 的研究结果。
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Understanding Oral Prep Interest Among South African Adolescents: The Role of Perceived Parental Support and PrEP Stigma.理解南非青少年对口腔准备的兴趣:感知到的父母支持和 PrEP 污名的作用。
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