Xuzhou Central Hospital, Xuzhou, Jiangsu, China.
University of California Berkeley, Berkeley, USA.
AIDS Behav. 2021 Mar;25(3):866-874. doi: 10.1007/s10461-020-03050-6. Epub 2020 Sep 28.
China's national guidelines call for increasing HIV pre-exposure prophylaxis (PrEP) use to reverse the epidemic in populations at highest risk. However, few data exist on PrEP awareness and willingness among trans women in China. Our research aim was to fill this data gap through a cross-sectional survey among trans women in Nanjing and Suzhou cities of Jiangsu province. Respondent-driven sampling (RDS) was used to recruit participants to gauge their awareness of and willingness to use PrEP. Logistic regression analysis was used to characterize associations with awareness of PrEP and willingness to use PrEP. Of 222 HIV-negative/unknown serostatus trans women, 33.3% were aware of PrEP and 49.1% were willing to use PrEP. PrEP awareness was associated with a university degree or above (adjusted odds ratio [AOR] 2.77, 95% CI 1.31-5.89) and not using alcohol with sex (AOR 2.02, 95% CI 1.00-4.09). Willingness to use PrEP was higher among trans women with one (AOR 3.56, 95% CI 1.68-7.54) or multiple sexual partners (AOR 2.53, 95% CI 1.24-5.15) compared to those with no partners. This study witnessed low awareness of PrEP, yet substantial willingness to use PrEP. Implementation research to identify ways to promote, scale up access, and assess effectiveness of PrEP for trans women is urgently needed in China.
中国的国家指南呼吁增加艾滋病毒暴露前预防 (PrEP) 的使用，以扭转高危人群中的疫情。然而，中国关于跨性别女性对 PrEP 的认识和意愿的数据很少。我们的研究目的是通过在江苏省南京市和苏州市的跨性别女性中进行横断面调查来填补这一数据空白。使用响应驱动抽样 (RDS) 招募参与者，以衡量他们对 PrEP 的认识和使用意愿。Logistic 回归分析用于描述与 PrEP 认识和使用意愿相关的特征。在 222 名 HIV 阴性/未知血清学状态的跨性别女性中，33.3%的人知道 PrEP，49.1%的人愿意使用 PrEP。PrEP 的认识与大学学历或以上有关（调整后的优势比 [AOR] 2.77，95%CI 1.31-5.89）和不用酒精与性接触有关（AOR 2.02，95%CI 1.00-4.09）。愿意使用 PrEP 的跨性别女性中，有一个（AOR 3.56，95%CI 1.68-7.54）或多个性伴侣（AOR 2.53，95%CI 1.24-5.15）的比例高于没有性伴侣的女性。这项研究见证了 PrEP 意识较低，但愿意使用 PrEP 的比例很高。迫切需要在中国开展实施研究，以确定促进、扩大获取和评估 PrEP 对跨性别女性有效性的方法。
