[辣木叶中的两种新黄酮苷]

[Two new flavonoid glycosides from leaves of Moringa oleifera].

作者信息

Ye Wei-Jian, Huang Xiao-Jun, Fan Chun-Lin, Xu Lin, Wang Ying, Ye Wen-Cai

机构信息

Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.

Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research， Jinan University， Guangzhou 510632， China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2018 Aug;43(15):3150-3156. doi: 10.19540/j.cnki.cjcmm.20180423.002.

DOI:10.19540/j.cnki.cjcmm.20180423.002

PMID:30200711

Abstract

Two new flavonoid glycosides, quercetin-3--(4--crotonyl)--D-glucopyranoside (1) and quercetin-3--[6--(2)-pentenoyl]--D-glucopyranoside (2), along with nine known ones, isoquercetin (3), astragalin (4), quercetin-3--(6--acetyl)--D-glucopyranoside (5), kaempferol-3--(6--acetyl)--D-glucopyranoside (6), quercetin-3--(6--crotonyl)--D-glucopyranoside (7), kaempferol-3--(6--crotonyl)--D-glucopyranoside (8), vitexin (9), isovitexin (10), and isorhamnetin-3---D-glucopyranoside (11), were isolated from the leaves of Moringa oleifera by various chromatographic technologies. Their structures were elucidated by spectroscopic methods including UV, IR, MS, and NMR. In addition, compounds 7 and 8 were isolated from this plant for the first time.

摘要

通过各种色谱技术从辣木叶中分离出两种新的黄酮苷，槲皮素 - 3 - - (4 - - 巴豆酰基) - - D - 吡喃葡萄糖苷（1）和槲皮素 - 3 - - [6 - - (2) - 戊烯酰基] - - D - 吡喃葡萄糖苷（2），以及九种已知的化合物，异槲皮苷（3）、紫云英苷（4）、槲皮素 - 3 - - (6 - - 乙酰基) - - D - 吡喃葡萄糖苷（5）、山柰酚 - 3 - - (6 - - 乙酰基) - - D - 吡喃葡萄糖苷（6）、槲皮素 - 3 - - (6 - - 巴豆酰基) - - D - 吡喃葡萄糖苷（7）、山柰酚 - 3 - - (6 - - 巴豆酰基) - - D - 吡喃葡萄糖苷（8）、牡荆素（9）、异牡荆素（10）和异鼠李素 - 3 - - D - 吡喃葡萄糖苷（11）。通过紫外光谱、红外光谱、质谱和核磁共振等光谱方法对它们的结构进行了鉴定。此外，化合物7和8首次从该植物中分离得到。