Li Feng-Hua, Wang Hong-Qing, Su Xian-Ming, Li Chang-Kang, Li Bao-Ming, Chen Ruo-Yun, Kang Jie
State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
Zhongguo Zhong Yao Za Zhi. 2018 Jan;43(1):114-118. doi: 10.19540/j.cnki.cjcmm.20171027.009.
Seventeen compounds were isolated from n-butanol extract of the leaves of Moringa oleifera, using column chromatography over macroporous resin HP-20,Sephadex LH-20, and ODS. Their structures were identified as two carboline,tangutorid E(1) and tangutorid F(2); three phenolic glycosides,niazirin(3),benzaldehyde 4-O-α-L-rhamnopyranoside(4) and 4-O-β-D-glucopyranosidebenzoic acid(5); four chlorogenic acid and derivatives,4-caffeoylquinic acid(6),methyl 4-caffeoylquinate(7),caffeoylquinic acid(8) and methyl caffeoylquinate(9); two nucleosids,uridine(10) and adenosine(11); one flavone,quercetin 3-O-β-D-glucopyranoside(12); five other types of compounds,phthalimidineacetic acid(13),3-pyridinecarboxamide(14),3,4-dihydroxy-benzoic acid(15),5-hydroxymethyl-2-furancarboxylic acid(16) and 5-hydroxymethyl-2-furaldehyde(17) by the spectral data of ¹H, ¹³C-NMR and MS. Among them,compounds 1-2,7,9-10,16 and 17 were isolated from M. oleifera for the first time.
采用大孔树脂HP - 20、葡聚糖凝胶LH - 20和ODS柱色谱法,从辣木叶的正丁醇提取物中分离得到17种化合物。通过¹H、¹³C - NMR和MS光谱数据鉴定其结构分别为两种咔啉类化合物,唐古特瑞林E(1)和唐古特瑞林F(2);三种酚苷,尼亚孜苷(3)、苯甲醛4 - O-α - L - 鼠李吡喃糖苷(4)和4 - O-β - D - 吡喃葡萄糖苷苯甲酸(5);四种绿原酸及其衍生物,4 - 咖啡酰奎尼酸(6)、4 - 咖啡酰奎尼酸甲酯(7)、咖啡酰奎尼酸(8)和咖啡酰奎尼酸甲酯(9);两种核苷,尿苷(10)和腺苷(11);一种黄酮,槲皮素3 - O-β - D - 吡喃葡萄糖苷(12);其他五种类型的化合物,邻苯二甲酰亚胺乙酸(13)、3 - 吡啶甲酰胺(14)、3,4 - 二羟基苯甲酸(15)、5 - 羟甲基 - 2 - 呋喃羧酸(16)和5 - 羟甲基 - 2 - 糠醛(17)。其中,化合物1 - 2、7、9 - 10、16和17为首次从辣木中分离得到。