Department of Asthma, Allergy and Immunology, Kaiser Permanente Colorado, Denver, Colo.
Institute for Health Research, Kaiser Permanente Colorado, Aurora, Colo.
J Allergy Clin Immunol Pract. 2019 Mar;7(3):908-914. doi: 10.1016/j.jaip.2018.08.029. Epub 2018 Sep 7.
Use of health technology has shown potential to improve asthma adherence and outcomes. Few studies have looked at the implementation of such research within larger asthma populations.
This report examines the process of translating results from a pragmatic trial using speech recognition (SR) in children with persistent asthma into the standard operating procedure within a large health maintenance organization. Medication adherence and outcomes in adults with asthma were examined.
The SR protocol was implemented for the total Kaiser Permanente Colorado (KPCO) patient population of 480,142, of whom 36,356 had asthma. Patients had persistent asthma, filled 1 or more inhaled corticosteroid prescriptions in the prior 6 months, and remained continuously enrolled with KPCO for 2 years. Documented exacerbations included the presence of a hospitalization, emergency department visit, or course of oral corticosteroid where asthma was the principal diagnosis. Adherence and exacerbation events were compared 1 year before and 1 year after intervention for 4,510 adults aged 19 to 64.
Patient adherence demonstrated a small but significant improvement from 39.5% to 41.7% (P < .0001). Although not significant, data trends suggested greater improvement for patients with lower socioeconomic status. When an outlier month was removed from both the pre- and postintervention time periods, courses of oral corticosteroids decreased. Emergency department visits and hospitalizations were infrequent in both time periods and did not decrease over time.
A low-cost SR intervention reminding patients to fill and take their daily controller asthma medication can improve treatment adherence and decrease the need for oral corticosteroids due to asthma exacerbations, but not decrease emergency department visits or hospitalizations.
使用医疗技术已显示出改善哮喘依从性和结果的潜力。很少有研究着眼于在更大的哮喘人群中实施此类研究。
本报告探讨了将使用语音识别(SR)治疗持续性哮喘儿童的实用试验结果转化为大型健康维护组织标准操作程序的过程。还检查了成年人哮喘的药物依从性和结果。
SR 方案在科罗拉多州 Kaiser Permanente(KPCO)的 480,142 名患者中实施,其中 36,356 名患者患有哮喘。患者患有持续性哮喘,在过去 6 个月内使用了 1 种或多种吸入皮质类固醇药物,并且在 KPCO 连续注册了 2 年。记录的恶化事件包括住院、急诊就诊或使用口服皮质类固醇的治疗,其中哮喘是主要诊断。在干预前 1 年和干预后 1 年,比较了 4,510 名年龄在 19 至 64 岁之间的成年人的依从性和恶化事件。
患者的依从性从 39.5%提高到 41.7%(P<0.0001),尽管不显著,但数据趋势表明,社会经济地位较低的患者改善更大。当从干预前后的时间段中删除异常月份时,口服皮质类固醇的疗程减少了。两个时间段的急诊就诊和住院就诊都很少见,且随时间推移没有减少。
一种低成本的 SR 干预措施,提醒患者每天服用和服用他们的哮喘控制药物,可以提高治疗依从性,并减少因哮喘恶化而需要口服皮质类固醇,但不能减少急诊就诊或住院治疗。