Ramamurthy V, Fleischmann R
J Gen Virol. 1986 Oct;67 ( Pt 10):2223-6. doi: 10.1099/0022-1317-67-10-2223.
The stability profiles of the antiviral states induced in L-929 cells against mengovirus by murine interferons MuIFN-alpha/beta and by MuIFN-gamma were shown to be different. Treatment of cells with combinations of IFN-alpha/beta and IFN-gamma have previously been shown to result in a potentiated expression of the antiviral state. Here we report studies of the stabilities of the antiviral states induced by various combinations of IFN-alpha/beta and IFN-gamma and that the regulation of the antiviral states induced by IFN-alpha/beta and IFN-gamma were independent of each other.
结果显示，小鼠干扰素MuIFN-α/β和MuIFN-γ在L-929细胞中诱导产生的抗脑心肌炎病毒状态的稳定性特征有所不同。此前研究表明，用IFN-α/β和IFN-γ组合处理细胞会导致抗病毒状态的增强表达。在此，我们报告了关于IFN-α/β和IFN-γ各种组合诱导产生的抗病毒状态稳定性的研究，以及IFN-α/β和IFN-γ诱导产生的抗病毒状态的调节彼此独立。
